Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 4/20 | 0.33 |
| ▸ | CDK6 | Q00534 | 4/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.31 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9890570 | 0.99 | CDK4 (0.33) | CDK4CDK6PDPK1TGFBR1IKBKE | |
| SCHEMBL9890116 | 0.92 | MAPT (0.33) | CDK4CDK6PDPK1TGFBR1IKBKE | |
| SCHEMBL9890445 | 0.91 | CDK4 (0.31) | CDK4CDK6NPC1MAPTKDM4E | |
| SCHEMBL9890378 | 0.91 | CDK4 (0.33) | CDK4CDK6PDPK1TGFBR1IKBKE | |
| SCHEMBL13529148 | 0.90 | CDK4 (0.31) | CDK4CDK6NPC1MAPTKDM4E | |
| SCHEMBL9890571 | 0.89 | DDB1 (0.37) | NPC1MAPTDDB1CRBNKDM4E | |
| SCHEMBL9890192 | 0.88 | CDK4 (0.33) | CDK4CDK6PDPK1TGFBR1IKBKE | |
| SCHEMBL13529162 | 0.87 | CDK4 (0.34) | CDK4CDK6IDO1 | |
| SCHEMBL9890574 | 0.86 | KDM4E (0.38) | CDK4CDK6KDM4EIDO1 | |
| SCHEMBL9890583 | 0.86 | NPC1 (0.36) | NPC1MAPTKDM4EALDH1A1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120138915-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2012-06-07 | — | — | US | disclosed |
| US-20120138915-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2012-06-07 | — | — | US | disclosed |