SCHEMBL989154

SCHEMBL989154

C=CCc1cnc2ccccc2n1

nearest known ligand 0.62

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 10/20 0.62
MEN1 O00255 1/20 0.53
MAPT P10636 1/20 0.53
KMT2A Q03164 1/20 0.53
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
HIF1A Q16665 1/20 0.41
KDM4E B2RXH2 2/20 0.39
GPR3 P46089 1/20 0.39
ALDH1A1 P00352 2/20 0.39
HPGD P15428 2/20 0.39
ALOX15 P16050 1/20 0.39
HSD17B10 Q99714 1/20 0.39
POLB P06746 1/20 0.39
GAA P10253 1/20 0.39
HTT P42858 1/20 0.38
PDGFRB P09619 1/20 0.38
PDGFRA P16234 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6265020 0.81 PDE10A (0.62) PDE10AMEN1MAPTKMT2ACYP1A2
SCHEMBL28287067 0.78 PDE10A (0.58) PDE10AMEN1MAPTKMT2ACYP1A2
SCHEMBL16826885 0.78 PDE10A (0.58) PDE10AMEN1MAPTKMT2ACYP1A2
SCHEMBL27594279 0.78 PDE10A (0.58) PDE10AMEN1MAPTKMT2ACYP1A2
SCHEMBL28668742 0.78 PDE10A (0.58) PDE10AMEN1MAPTKMT2ACYP1A2
SCHEMBL29183171 0.78 PDE10A (0.58) PDE10AMEN1MAPTKMT2ACYP1A2
SCHEMBL5247878 0.78 PDE10A (0.69) PDE10AMEN1MAPTKMT2ACYP1A2
SCHEMBL752676 0.78 PDE10A (0.69) PDE10AMEN1MAPTKMT2ACYP1A2
SCHEMBL9112576 0.78 PDE10A (0.53) PDE10AMEN1MAPTKMT2ACYP1A2
SCHEMBL12066225 0.77 PDE10A (1.00) PDE10AMEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 237 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3138890-B1 AGGREGATING COMPOSITIONS, MODIFIED PARTICULATE METAL OXIDES, MODIFIED FORMATION SURFACES, AND METHODS FOR MAKING AND USING SAME LUBRIZOL CORP (US) 2020-11-11 EP claimed
EP-3071666-B1 METHOD AND COMPOSITION FOR CONSOLIDATING SOLID MATERIALS DURING SUBTERRANEAN TREATMENT OPERATIONS LUBRIZOL CORP (US) 2020-08-12 EP claimed
CN-105745300-B Method of consolidating solid materials during subterranean treatment operations 韦特福特科技控股有限责任公司 2019-10-22 CN claimed
EP-3486296-A1 A METHOD AND SYSTEM USING ZETA POTENTIAL ALTERING COMPOSITIONS AS AGGREGATING REAGENTS FOR SAND CONTROL The Lubrizol Corporation (US) 2019-05-22 EP claimed
CN-109608406-A A kind of nitro alkyl quinoxaline or derivatives thereof, aminoalkyl quinoxaline or derivatives thereof and its synthetic method 上海交通大学 2019-04-12 CN claimed
US-10202836-B2 Methods for fracturing formations using aggregating compositions THE LUBRIZOL CORPORATION (US) 2019-02-12 US claimed
US-10040991-B2 Zeta potential modifiers to decrease the residual oil saturation THE LUBRIZOL CORPORATION (US) 2018-08-07 US claimed
US-20180209260-A1 Method to Consolidate Solid Materials During Subterranean Treatment Operations LUBRIZOL CORP (US) 2018-07-26 US claimed
EP-3303504-A1 AGGREGATING COMPOSITIONS, MODIFIED PARTICULATE SOLID COMPOSITIONS, AND METHODS FOR MAKING AND USING SAME Lubrizol Oilfield Solutions, Inc. (US) 2018-04-11 EP claimed
US-9938453-B2 Particulate aggregating and surface modification with improved hydrocarbon fluid flow through the aggregated particulates and over solid surface reagents and methods for making and using same Sumisaujana TCM Chemicals Sdn. Bhd. (MY) 2018-04-10 US claimed
US-20100292108-A1 AGGREGATING COMPOSITIONS, MODIFIED PARTICULATE METAL-OXIDES, MODIFIED FORMATION SURFACES, AND METHODS FOR MAKING AND USING SAME CLEARWATER INTERNATIONAL, LLC (US) 2010-11-18 US claimed
EP-2251394-A2 Aggregating compositions, modified particulate metal-oxides, modified formation surfaces, and methods for making and using same Clearwater International LLC (US) 2010-11-17 EP claimed
EP-2251395-A1 Methods for increase gas production and load recovery Clearwater International LLC (US) 2010-11-17 EP claimed
US-20100212905-A1 METHOD AND SYSTEM USING ZETA POTENTIAL ALTERING COMPOSITIONS AS AGGREGATING REAGENTS FOR SAND CONTROL WEATHERFORD/LAMB, INC. (US) 2010-08-26 US claimed
WO-2010084009-A1 A METHOD AND SYSTEM USING ZETA POTENTIAL ALTERING COMPOSITIONS AS AGGREGATING REAGENTS FOR SAND CONTROL WEATHERFORD/LAMB, INC (US) 2010-07-29 WO claimed
CN-101775123-A Polyfluorene conjugated polymer with thiophene and other aromatic heterocycle at C9 side chain, and preparation method and applications thereof UNIV SOUTH CHINA NORMAL 2010-07-14 CN claimed
US-20090275488-A1 METHODS FOR INCREASE GAS PRODUCTION AND LOAD RECOVERY CLEARWATER INTERNATIONAL, LLC (US) 2009-11-05 US claimed
US-20080257553-A1 Aggregating reagents, modified particulate metal-oxides and proppants CLEARWATER INTERNATIONAL, LLC 2008-10-23 US claimed
US-7392847-B2 Aggregating reagents, modified particulate metal-oxides, and methods for making and using same CLEARWATER INTERNATIONAL, LLC (US) 2008-07-01 US claimed
US-20070131425-A1 Aggregating reagents, modified particulate metal-oxides, and methods for making and using same CLEARWATER INTERNATIONAL, LLC 2007-06-14 US claimed