Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 15/20 | 0.87 |
| ▸ | CNR1 | P21554 | 7/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9892167 | 0.93 | CNR2 (1.00) | CNR2CNR1TSHRMEN1CYP1A2 | |
| SCHEMBL13256991 | 0.92 | CNR2 (0.94) | CNR2CNR1TSHRMEN1CYP1A2 | |
| SCHEMBL9892062 | 0.84 | CNR2 (0.70) | CNR2CNR1TSHRMEN1CYP1A2 | |
| SCHEMBL9892170 | 0.84 | CNR2 (0.85) | CNR2CNR1TSHRMEN1CYP1A2 | |
| SCHEMBL13256830 | 0.83 | CNR2 (0.79) | CNR2CNR1TSHRMEN1CYP1A2 | |
| SCHEMBL9892171 | 0.83 | CNR2 (0.83) | CNR2CNR1TSHRMEN1CYP1A2 | |
| SCHEMBL9892168 | 0.83 | CNR2 (0.83) | CNR2CNR1TSHRMEN1CYP1A2 | |
| SCHEMBL13257833 | 0.83 | CNR2 (0.79) | CNR2CNR1TSHRMEN1CYP1A2 | |
| SCHEMBL9892172 | 0.82 | CNR2 (0.81) | CNR2CNR1TSHRMEN1CYP1A2 | |
| SCHEMBL13256835 | 0.82 | CNR2 (0.78) | CNR2CNR1TSHRMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383615-B2 | Azetidine 2-carboxamide derivatives which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-02-26 | — | — | US | disclosed |
| US-20120142666-A1 | Azetidine 2-Carboxamide Derivatives Which Modulate The CB2 Receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142666-A1 | Azetidine 2-Carboxamide Derivatives Which Modulate The CB2 Receptor | CNR2, CNR1, OPRL1 | CNR2 1/4885CNR1 2/4885TSHR 1019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.