SCHEMBL989420

SCHEMBL989420

BrN1C=CC=CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17800647 0.69
SCHEMBL589950 0.67
SCHEMBL6436447 0.63
SCHEMBL5435337 0.63
SCHEMBL3325785 0.63
SCHEMBL1327501 0.62
Hydrochloric Acid SCHEMBL1071446 0.62
SCHEMBL5579335 0.62
SCHEMBL8052784 0.62
SCHEMBL7348642 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240351966-A1 CLASS OF ALKYLPHENOL COMPOUNDS AND PREPARATION METHOD THEREFOR SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) 2024-10-24 US disclosed
WO-2024216750-A1 METAL COMPLEX AND ORGANIC ELECTROLUMINESCENT DEVICE 深圳大学 2024-10-24 WO disclosed
CN-118620000-A Metal complex and organic electroluminescent device 深圳大学 2024-09-10 CN disclosed
EP-4353706-A1 CLASS OF ALKYLPHENOL COMPOUNDS AND PREPARATION METHOD THEREFOR Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) 2024-04-17 EP disclosed
CN-115322077-B Alkylphenol compounds and preparation method thereof 中国科学院上海药物研究所 2024-03-15 CN disclosed
CN-116804001-A Quinazolinone derivative containing pyridinium and preparation method and application thereof 江苏海洋大学 2023-09-26 CN disclosed
CN-116675718-A Metal complex and organic electroluminescent device 深圳大学 2023-09-01 CN disclosed
WO-2022237852-A1 CLASS OF ALKYLPHENOL COMPOUNDS AND PREPARATION METHOD THEREFOR 中国科学院上海药物研究所 2022-11-17 WO disclosed
CN-115322077-A Alkylphenol compounds and preparation method thereof 中国科学院上海药物研究所 2022-11-11 CN disclosed
CN-114867735-A RAS inhibitors 锐新医药公司 2022-08-05 CN disclosed
US-20030059646-A1 Luminescence device and display apparatus CANON KABUSHIKI KAISHA (JP) 2003-03-27 US disclosed
EP-0754176-B1 NOVEL CARBAMATES AND UREAS AS MODIFIERS OF MULTI-DRUG RESISTANCE VERTEX PHARMA (US) 2001-12-05 EP disclosed
EP-1138673-A2 Novel carbamates and ureas as modifiers of multi-drug resistance Vertex Pharmaceuticals Incorporated (US) 2001-10-04 EP disclosed
CN-1239434-A Methods and compsns. for stimulating neurite growth using compounds with affinity for FKBP12 in combination with neurotrophic factors VERTED PHARMACEUTICALS INC (US) 1999-12-22 CN disclosed
EP-0941113-A1 METHODS AND COMPOSITIONS FOR STIMULATING NEURITE GROWTH USING COMPOUNDS WITH AFFINITY FOR FKBP12 IN COMBINATION WITH NEUROTROPHIC FACTORS Vertex Pharmaceuticals Incorporated (US) 1999-09-15 EP disclosed
US-5780484-A Methods for stimulating neurite growth with piperidine compounds VERTEX PHARMACEUTICALS INCORPORATED (US) 1998-07-14 US disclosed
WO-1998020893-A1 METHODS AND COMPOSITIONS FOR STIMULATING NEURITE GROWTH USING COMPOUNDS WITH AFFINITY FOR FKBP12 IN COMBINATION WITH NEUROTROPHIC FACTORS VERTEX PHARMACEUTICALS INCORPORATED (US) 1998-05-22 WO disclosed
US-5744485-A INCREASE SENSITIVITY OF CELLS; CANCER VERTEX PHARMACEUTICALS INCORPORATED (US) 1998-04-28 US disclosed
EP-0754176-A1 NOVEL CARBAMATES AND UREAS AS MODIFIERS OF MULTI-DRUG RESISTANCE Vertex Pharmaceuticals Incorporated (US) 1997-01-22 EP disclosed
WO-1995026337-A1 NOVEL CARBAMATES AND UREAS AS MODIFIERS OF MULTI-DRUG RESISTANCE VERTEX PHARMACEUTICALS INCORPORATED (US) 1995-10-05 WO disclosed