SCHEMBL989728

SCHEMBL989728

CC(F)CBr

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9971585 0.75
SCHEMBL28210028 0.75
SCHEMBL31306 0.72
SCHEMBL20957496 0.72
SCHEMBL18631346 0.72
SCHEMBL30733 0.70
SCHEMBL7399 0.70
SCHEMBL14127280 0.70
SCHEMBL4730315 0.70
SCHEMBL8020741 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0813609-B1 METHOD OF NUCLEIC ACID ANALYSIS CANCER REC TECH LTD (GB) 2004-10-13 EP claimed
US-6268129-B1 MASS SPECTROMETRY OF CHARGED NUCLEIC ACID; DNA SEQUENCING IMPERIAL CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2001-07-31 US claimed
EP-0813609-A1 METHOD OF NUCLEIC ACID ANALYSIS IMPERIAL CANCER RESEARCH TECHNOLOGY LIMITED (GB) 1997-12-29 EP claimed
WO-1996027681-A1 METHOD OF NUCLEIC ACID ANALYSIS IMPERIAL CANCER RESEARCH TECHNOLOGY LIMITED (GB) 1996-09-12 WO claimed
JP-11322655-A None JP disclosed
CN-111954848-B Photosensitive resin composition, cured product, insulating material, resin material for solder resist, and resist member DIC株式会社 2024-05-03 CN disclosed
US-20220227728-A1 Microtubule-associated protein Tau imaging compounds for Alzheimer's disease and precursors thereof LI MING HSIN (TW) 2022-07-21 US disclosed
CN-109153653-B Novel compound, photocurable composition, cured product thereof, printing ink, and printed matter using the printing ink DIC株式会社 2022-06-28 CN disclosed
US-20210338849-A1 COMPOUNDS AND COMPOSITIONS FOR THE DETECTION AND TREATMENT OF ALZHEIMER'S DISEASE AND RELATED DISORDERS MASSACHUSETTS GEN HOSPITAL (US) 2021-11-04 US disclosed
US-11079675-B2 Compound, photocurable composition, cured product of same, printing ink, and printed matter curing the printing ink DIC CORPORATION (JP) 2021-08-03 US disclosed
EP-3231804-B1 COMPOUNDS AND COMPOSITIONS FOR THE DETECTION AND TREATMENT OF ALZHEIMER'S DISEASE AND RELATED DISORDERS MASSACHUSETTS GEN HOSPITAL (US) 2021-03-03 EP disclosed
US-10857247-B2 Compounds and compositions for the detection and treatment of Alzheimer's disease and related disorders THE GENERAL HOSPITAL CORPORATION (US) 2020-12-08 US disclosed
WO-1996027681-A1 METHOD OF NUCLEIC ACID ANALYSIS IMPERIAL CANCER RESEARCH TECHNOLOGY LIMITED (GB) 1996-09-12 WO disclosed
CN-1097736-A New anti-arrhythmic agents and preparation method thereof HAESSLE AB (SE) 1995-01-25 CN disclosed
WO-1994006783-A1 BENZOXAZOLE AND BENZOTHIAZOLE DERIVATIVES ZENECA LIMITED (GB) 1994-03-31 WO disclosed
EP-0322390-B1 NOVEL ANTIARRHYTHMIC AGENTS I Aktiebolaget Hässle (SE) 1992-11-11 EP disclosed
US-5155133-A Antiarrhythmic compounds and pharmaceutical compositions and methods thereof AKTIEBOLAGET HASSLE (SE) 1992-10-13 US disclosed
CN-1033804-A Novel antiarrhythmic agents and process for their preparation HAESSLE AB (SE) 1989-07-12 CN disclosed
WO-1989005794-A1 NOVEL ANTIARRHYTHMIC AGENTS I Aktiebolaget Hässle (SE) 1989-06-29 WO disclosed
EP-0322390-A2 Novel antiarrhythmic agents I Aktiebolaget Hässle (SE) 1989-06-28 EP disclosed