⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9596 | 0.97 | — | — | |
| Water SCHEMBL14333714 | 0.94 | — | — | |
| SCHEMBL9813332 | 0.94 | — | — | |
| SCHEMBL30982431 | 0.94 | — | — | |
| Potassium SCHEMBL31456747 | 0.94 | — | — | |
| SCHEMBL25414048 | 0.94 | — | — | |
| SCHEMBL1149107 | 0.94 | — | — | |
| SCHEMBL8004964 | 0.94 | — | — | |
| Methane SCHEMBL22588025 | 0.94 | — | — | |
| SCHEMBL31556086 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150376817-A1 | OXYGEN AND NITROGEN CO-DOPED POLYACRYLONITRILE-BASED CARBON FIBER AND PREPARATION METHOD THEREOF | OCEAN UNIVERSITY OF CHINA (CN) | 2015-12-31 | — | — | US | claimed |
| WO-2026107371-A2 | INDOLYL-PYRIDINONES AND RELATED COMPOUNDS AND THEIR USE IN THERAPY | HOTSPOT THERAPEUTICS, INC. (US) | 2026-05-21 | — | — | WO | disclosed |
| US-10010536-B2 | Method of modulating stress-activated protein kinase system | INTERMUNE, INC. (US) | 2018-07-03 | — | — | US | disclosed |
| US-20170095462-A1 | METHOD OF MODULATING STRESS-ACTIVATED PROTEIN KINASE SYSTEM | INTERMUNE, INC. | 2017-04-06 | — | — | US | disclosed |
| US-9527816-B2 | Method of modulating stress-activated protein kinase system | INTERMUNE, INC. (US) | 2016-12-27 | — | — | US | disclosed |
| EP-2591784-B1 | Pyridine-2-one-derivatives as modulators of stress-activated protein kinase system | INTERMUNE INC (US) | 2016-09-14 | — | — | EP | disclosed |
| EP-1928454-B1 | PYRIDONE DERIVATIVES FOR MODULATING STRESS-ACTIVATED PROTEIN KINASE SYSTEM | INTERMUNE INC (US) | 2014-09-24 | — | — | EP | disclosed |
| US-20140228310-A1 | METHOD OF MODULATING STRESS-ACTIVATED PROTEIN KINASE SYSTEM | INTERMUNE, INC. (US) | 2014-08-14 | — | — | US | disclosed |
| US-8741936-B2 | Method of modulating stress-activated protein kinase system | INTERMUNE, INC. (US) | 2014-06-03 | — | — | US | disclosed |
| EP-2591784-A1 | Pyridine-2-one-derivatives as modulators of stress-activated protein kinase system | Intermune, Inc. (US) | 2013-05-15 | — | — | EP | disclosed |
| US-20060270612-A1 | Method of modulating stress-activated protein kinase system | INTERMUNE, INC. | 2006-11-30 | — | — | US | disclosed |
| WO-2006122154-A2 | PYRIDONE DERIVATIVES FOR MODULATING STRESS-ACTIVATED PROTEIN KINASE SYSTEM | INTERMUNE, INC. (US) | 2006-11-16 | — | — | WO | disclosed |
| US-7125888-B2 | Tyrosine kinase inhibitors | MERCK & CO., INC. (US) | 2006-10-24 | — | — | US | disclosed |
| EP-1503757-A4 | TYROSINE KINASE INHIBITORS | MERCK & CO INC (US) | 2005-11-16 | — | — | EP | disclosed |
| US-20050176753-A1 | controlling signal transduction; anticancer agents; antitumor agnets; atherosclerosis; vision defects; antidiabetic agents; antiinflammatory agents | MERCK SHARP & DOHME CORP. | 2005-08-11 | — | — | US | disclosed |
| EP-1503757-A2 | TYROSINE KINASE INHIBITORS | Merck & Co., Inc. (US) | 2005-02-09 | — | — | EP | disclosed |
| WO-2003092595-A2 | TYROSINE KINASE INHIBITORS | MERCK & CO., INC (US) | 2003-11-13 | — | — | WO | disclosed |
| US-6565828-B2 | Bifunctional chelant for attaching diagnostic metals and therpeutic isotopes to target specific biomolecules; heavy metal detoxification | BRISTOL-MYERS SQUIBB COMPANY | 2003-05-20 | — | — | US | disclosed |
| US-20020004032-A1 | Macrocyclic chelants for metallopharmaceuticals | LANTHEUS MEDICAL IMAGING, INC. | 2002-01-10 | — | — | US | disclosed |
| WO-2001077102-A1 | MACROCYCLIC CHELANTS FOR METALLOPHARMACEUTICALS | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2001-10-18 | — | — | WO | disclosed |