Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | GCGR | P47871 | 9/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | RAPGEF3 | O95398 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL205772 | 0.90 | TRPV1 (0.42) | TRPV1EPHX2NR1H4TRPM8DHODH | |
| SCHEMBL9896548 | 0.90 | TRPV1 (0.41) | TRPV1DHODHGCGRMCHR1RAPGEF3 | |
| SCHEMBL9894697 | 0.89 | TRPV1 (0.41) | TRPV1DHODHGCGRMCHR1RAPGEF3 | |
| SCHEMBL205272 | 0.87 | TRPV1 (0.44) | TRPV1DHODHGCGRRAPGEF3 | |
| SCHEMBL202741 | 0.86 | TRPV1 (0.45) | TRPV1DHODHGCGRRAPGEF3 | |
| SCHEMBL205432 | 0.85 | TRPV1 (0.43) | TRPV1DHODHGCGRRAPGEF3 | |
| SCHEMBL205770 | 0.85 | TRPV1 (0.42) | TRPV1DHODHGCGRRAPGEF3 | |
| SCHEMBL203091 | 0.85 | TRPV1 (0.42) | TRPV1DHODHGCGRRAPGEF3 | |
| SCHEMBL9897779 | 0.83 | GCGR (0.40) | TRPV1EPHX2NR1H4DHODHGCGR | |
| SCHEMBL204709 | 0.82 | TRPV1 (0.46) | TRPV1EPHX2NR1H4DHODHGCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149750-A1 | ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF | MERIAL, INC. | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149750-A1 | ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF | CYP4X1, CBR3, TYR | TRPV1 4024/4885EPHX2 403/4885NR1H4 4140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.