⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL27913319 | 0.97 | — | — | |
| Iodide SCHEMBL28281005 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL8498790 | 0.94 | TRIM24 (0.35) | — | |
| SCHEMBL3345097 | 0.84 | — | — | |
| SCHEMBL10932455 | 0.69 | TRIM24 (0.41) | — | |
| SCHEMBL4650647 | 0.69 | TRIM24 (0.41) | — | |
| SCHEMBL83690 | 0.69 | — | — | |
| SCHEMBL119955 | 0.68 | — | — | |
| SCHEMBL7981543 | 0.68 | — | — | |
| SCHEMBL242394 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101857565-A | Preparation method of 3-amino-4-piperidone and corresponding derivative thereof | WUXI APPTEC SHANGHAI CO LTD | 2010-10-13 | — | — | CN | claimed |
| US-20210395406-A1 | REVERSIBLE CROSS-LINKING SYSTEM FOR POLYVINYLAMINES | SOLENIS TECHNOLOGIES, L.P. | 2021-12-23 | — | — | US | disclosed |
| US-20200078353-A1 | OLIGOMER-OPIOID AGONIST CONJUGATES | INHERIS BIOPHARMA INC (US) | 2020-03-12 | — | — | US | disclosed |
| US-20190247388-A1 | OLIGOMER-OPIOID AGONIST CONJUGATES | NEKTAR THERAPEUTICS | 2019-08-15 | — | — | US | disclosed |
| US-10307416-B2 | Oligomer-opioid agonist conjugates | NEKTAR THERAPEUTICS (US) | 2019-06-04 | — | — | US | disclosed |
| US-20190046523-A1 | OLIGOMER-OPIOID AGONIST CONJUGATES | NEKTAR THERAPEUTICS | 2019-02-14 | — | — | US | disclosed |
| US-10143690-B2 | Oligomer-opioid agonist conjugates | NEKTAR THERAPEUTICS (US) | 2018-12-04 | — | — | US | disclosed |
| US-20180296550-A1 | Compositions, Dosage Forms, and Co-Administration of an Opioid Agonist Compound and an Analgesic Compound | NEKTAR THERAPEUTICS | 2018-10-18 | — | — | US | disclosed |
| US-20180256563-A1 | OLIGOMER-OPIOID AGONIST CONJUGATES | NEKTAR THERAPEUTICS | 2018-09-13 | — | — | US | disclosed |
| US-9925182-B2 | Compositions, dosage forms, and co-administration of an opioid agonist compound and an analgesic compound | NEKTAR THERAPEUTICS (US) | 2018-03-27 | — | — | US | disclosed |
| WO-2011011543-A1 | OLIGOMER-OPIOID AGONIST CONJUGATES | NEKTAR THERAPEUTICS (US) | 2011-01-27 | — | — | WO | disclosed |
| CN-101857565-A | Preparation method of 3-amino-4-piperidone and corresponding derivative thereof | WUXI APPTEC SHANGHAI CO LTD | 2010-10-13 | — | — | CN | disclosed |
| US-20100048602-A1 | Oligomer-Opioid Agonist Conjugates | NEKTAR THERAPEUTICS (US) | 2010-02-25 | — | — | US | disclosed |
| WO-2009123986-A1 | APOPTOSIS SIGNAL-REGULATING KINASE 1 INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-08 | — | — | WO | disclosed |
| WO-2008134354-A1 | TNF-α PRODUCTION INHIBITOR | ARRAY BIOPHARMA, INC. (US) | 2008-11-06 | — | — | WO | disclosed |
| EP-1946777-A1 | Substituted pyrazoline for preventing weight gain | Laboratorios del Dr. Esteve S.A. (ES) | 2008-07-23 | — | — | EP | disclosed |
| EP-1946778-A1 | Active substance combination for the treatment of diabetes | Laboratorios del Dr. Esteve S.A. (ES) | 2008-07-23 | — | — | EP | disclosed |
| EP-1910302-A1 | CARBONYL SUBSTITUTED PYRAZOLINE COMPOUNDS, THEIR PREPARATION AND USE AS CB1 RECEPTOR MODULATORS | Laboratorios del Dr. Esteve S.A. (ES) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007009687-A1 | CARBONYL SUBSTITUTED PYRAZOLINE COMPOUNDS, THEIR PREPARATION AND USE AS CB1 RECEPTOR MODULATORS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-01-25 | — | — | WO | disclosed |
| US-20070021398-A1 | Substituted Pyrazoline Compounds, their Preparation and Use as Medicaments | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-01-25 | — | — | US | disclosed |