SCHEMBL9900465

SCHEMBL9900465

O=C(CCC(=NOCc1ccccc1)c1ccccc1)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 1/20 0.49
PPARA Q07869 6/20 0.48
TDP1 Q9NUW8 3/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
CASP3 P42574 1/20 0.47
SENP8 Q96LD8 1/20 0.47
SENP7 Q9BQF6 1/20 0.47
SENP6 Q9GZR1 1/20 0.47
ALDH1A1 P00352 3/20 0.46
PPARG P37231 5/20 0.46
GAA P10253 1/20 0.45
CYP2C19 P33261 1/20 0.45
SLC6A2 P23975 1/20 0.45
SLC6A3 Q01959 1/20 0.45
KMT2A Q03164 1/20 0.45
L3MBTL1 Q9Y468 2/20 0.44
LMNA P02545 2/20 0.44
MAPT P10636 2/20 0.44
MMP2 P08253 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9900464 1.00 NR4A2 (0.49) NR4A2PPARATDP1NPC1RAB9A
SCHEMBL9898401 0.91 TDP1 (0.53) NR4A2PPARATDP1NPC1RAB9A
SCHEMBL9898400 0.91 TDP1 (0.53) NR4A2PPARATDP1NPC1RAB9A
SCHEMBL2043173 0.90 PPARA (0.48) PPARATDP1NPC1RAB9AALDH1A1
SCHEMBL2043176 0.90 PPARA (0.48) PPARATDP1NPC1RAB9AALDH1A1
SCHEMBL2047384 0.83 PPARA (0.46) PPARATDP1NPC1RAB9AALDH1A1
SCHEMBL2047385 0.83 PPARA (0.46) PPARATDP1NPC1RAB9AALDH1A1
SCHEMBL9898562 0.83 NR4A2 (0.47) NR4A2PPARATDP1NPC1RAB9A
SCHEMBL9898564 0.83 NR4A2 (0.47) NR4A2PPARATDP1NPC1RAB9A
SCHEMBL9897839 0.82 KMT2A (0.46) PPARATDP1NPC1RAB9ACASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8748531-B2 Polymers functionalized with oxime compounds containing an acyl group BRIDGESTONE CORPORATION (JP) 2014-06-10 US claimed
EP-2649102-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP Bridgestone Corporation (JP) 2013-10-16 EP claimed
US-20120149833-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORPORATION (JP) 2012-06-14 US claimed
WO-2012078962-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORPORATION (JP) 2012-06-14 WO claimed
EP-2649102-B1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORP (JP) 2014-11-26 EP disclosed
US-8748531-B2 Polymers functionalized with oxime compounds containing an acyl group BRIDGESTONE CORPORATION (JP) 2014-06-10 US disclosed
US-20120149833-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORPORATION (JP) 2012-06-14 US disclosed