Bicarbonate

Bicarbonate

SCHEMBL9901065

CCc1[nH]cc[n+]1C.O=C([O-])O

nearest known ligand 0.31

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL302240 0.93
Propionic Acid SCHEMBL528119 0.91
Oxalic Acid SCHEMBL17729888 0.91
Oxalic Acid SCHEMBL3762279 0.88
Glycine SCHEMBL9901333 0.88
Trifluoroacetic Acid SCHEMBL535086 0.86 NPC1 (0.31)
L-Lactic Acid SCHEMBL3641892 0.86
SCHEMBL158886 0.86
Alanine SCHEMBL16346438 0.85
Hydrochloric Acid SCHEMBL367559 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3200804-A1 POLYSACCHARIDE AND NUCLEIC ACID FORMULATIONS CONTAINING VISCOSITY-LOWERING AGENTS Eagle Biologics, Inc. (US) 2017-08-09 EP disclosed
EP-3043774-A2 LIQUID PROTEIN FORMULATIONS CONTAINING IONIC LIQUIDS Arsia Therapeutics, Inc. (US) 2016-07-20 EP disclosed
WO-2016054259-A1 POLYSACCHARIDE AND NUCLEIC ACID FORMULATIONS CONTAINING VISCOSITY-LOWERING AGENTS Arsia Therapeutics, Inc. (US) 2016-04-07 WO disclosed
WO-2015038811-A2 LIQUID PROTEIN FORMULATIONS CONTAINING IONIC LIQUIDS Arsia Therapeutics, Inc. (US) 2015-03-19 WO disclosed
WO-2012078783-A2 IMMOBILIZATION OF IONIC LIQUIDS VIA MECHNOCHEMICAL INTERCALATION IN LAYERED MATERIALS TEXAS STATE UNIVERSITY-SAN MARCOS (US) 2012-06-14 WO disclosed