Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 4/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9902819 | 0.93 | KDM4E (0.34) | KDM4EGAAKMT2AARSLC6A2 | |
| SCHEMBL9902168 | 0.88 | AR (0.32) | ARSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9902171 | 0.88 | AR (0.32) | ARSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL16994493 | 0.88 | KDM4E (0.39) | KDM4EGAAKMT2ACA1CA2 | |
| SCHEMBL9902438 | 0.88 | KDM4E (0.41) | KDM4EGAAKMT2AARCA1 | |
| SCHEMBL16994518 | 0.85 | KDM4E (0.51) | KDM4EGAAKMT2ACA1CA2 | |
| SCHEMBL9902402 | 0.84 | KDM4E (0.37) | KDM4EGAAKMT2ASLC6A2SLC6A4 | |
| SCHEMBL18727708 | 0.83 | EGFR (0.36) | KDM4EGAAKMT2ACA1CA2 | |
| SCHEMBL18727707 | 0.83 | EGFR (0.36) | KDM4EGAAKMT2ACA1CA2 | |
| SCHEMBL9902154 | 0.82 | KDM4E (0.38) | KDM4EGAAKMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |