Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CCR1 | P32246 | 3/20 | 0.45 |
| ▸ | CCR5 | P51681 | 3/20 | 0.45 |
| ▸ | CCR8 | P51685 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.40 |
| ▸ | NPC1 | O15118 | 7/20 | 0.40 |
| ▸ | RAB9A | P51151 | 7/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1314692 | 0.87 | NOTUM (0.62) | CA12CA9NOTUMKDM4ELMNA | |
| SCHEMBL31434715 | 0.87 | NOTUM (0.62) | CA12CA9NOTUMKDM4ELMNA | |
| SCHEMBL9901314 | 0.84 | CA12 (0.47) | CA12CA9NOTUMKDM4ELMNA | |
| SCHEMBL26527466 | 0.80 | CA12 (0.49) | CA12CA9NOTUMKDM4ELMNA | |
| SCHEMBL9901587 | 0.80 | CA12 (0.49) | CA12CA9NOTUMKDM4ELMNA | |
| SCHEMBL2120922 | 0.80 | NOTUM (0.62) | CA12CA9NOTUMKDM4ELMNA | |
| SCHEMBL8938531 | 0.80 | CA12 (0.49) | CA12CA9NOTUMKDM4ELMNA | |
| SCHEMBL28941884 | 0.79 | CA12 (0.46) | CA12CA9NOTUMKDM4ELMNA | |
| SCHEMBL23881749 | 0.78 | NOTUM (0.74) | NOTUMLMNACYP1A2POLBSMN1; SMN2 | |
| SCHEMBL6705332 | 0.76 | CA12 (0.46) | CA12CA9NOTUMKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2673285-A1 | KETOLIDE COMPOUNDS | Wockhardt Limited (IN) | 2013-12-18 | — | — | EP | disclosed |
| WO-2012076989-A1 | KETOLIDE COMPOUNDS | WOCKHARDT LIMITED (IN) | 2012-06-14 | — | — | WO | disclosed |
| US-3956343-A | ANTIINFLAMMATORY AGENT | AMERICAN CYANAMID COMPANY (US) | 1976-05-11 | — | — | US | disclosed |