Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2330634 | 0.85 | MEN1 (0.63) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL16554034 | 0.84 | KMT2A (0.58) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL3634417 | 0.83 | MEN1 (0.57) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL625332 | 0.83 | MEN1 (0.57) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL362584 | 0.82 | MEN1 (0.56) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL14626678 | 0.82 | MEN1 (0.56) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL13310876 | 0.82 | MEN1 (0.56) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL25057561 | 0.81 | KMT2A (0.54) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL20995023 | 0.80 | MEN1 (0.57) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL5370952 | 0.79 | KMT2A (0.53) | KMT2AMEN1MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4567265-A | REACTING 2-NITROPROPANE WITH UNSATURATED CYANOESTER | LOYOLA UNIVERSITY OF CHICAGO (US) | 1986-01-28 | — | — | US | claimed |
| EP-2268647-A2 | COMPOUNDS AND COMPOSITIONS FOR THE DETECTION AND TREATMENT OF ALZHEIMER'S DISEASE AND RELATED DISORDERS | The General Hospital Corporation (US) | 2011-01-05 | — | — | EP | disclosed |
| US-4567265-A | REACTING 2-NITROPROPANE WITH UNSATURATED CYANOESTER | LOYOLA UNIVERSITY OF CHICAGO (US) | 1986-01-28 | — | — | US | disclosed |