Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.35 |
| ▸ | EED | O75530 | 2/20 | 0.35 |
| ▸ | RBBP4 | Q09028 | 2/20 | 0.35 |
| ▸ | SUZ12 | Q15022 | 2/20 | 0.35 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.35 |
| ▸ | AEBP2 | Q6ZN18 | 2/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9902442 | 0.84 | BRD4 (0.37) | BRD4CREBBPEEDRBBP4SUZ12 | |
| SCHEMBL9902244 | 0.83 | BRD4 (0.35) | BRD4CREBBPEEDRBBP4SUZ12 | |
| SCHEMBL9903900 | 0.82 | NAMPT (0.37) | BRD4CREBBPEEDRBBP4SUZ12 | |
| SCHEMBL9903797 | 0.81 | BRD4 (0.36) | BRD4CREBBPEEDRBBP4SUZ12 | |
| SCHEMBL9903184 | 0.81 | BRD4 (0.36) | BRD4CREBBPEEDRBBP4SUZ12 | |
| Hydrochloric Acid SCHEMBL11893788 | 0.80 | BRD4 (0.35) | BRD4CREBBPEEDRBBP4SUZ12 | |
| Hydrochloric Acid SCHEMBL11894045 | 0.80 | BRD4 (0.35) | BRD4CREBBPEEDRBBP4SUZ12 | |
| SCHEMBL9903878 | 0.80 | USP2 (0.41) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL9903744 | 0.76 | BRD4 (0.40) | BRD4CREBBPNAMPTUSP30SMN1; SMN2 | |
| SCHEMBL9902640 | 0.74 | BRD4 (0.40) | BRD4CREBBPUSP30GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8916549-B2 | Thienooxazepine derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2014-12-23 | — | — | US | disclosed |
| EP-2463290-B1 | THIENOOXAZEPINE DERIVATIVE | TAKEDA PHARMACEUTICAL (JP) | 2014-03-05 | — | — | EP | disclosed |
| US-20120196848-A1 | THIENOOXAZEPINE DERIVATIVE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-08-02 | — | — | US | disclosed |
| EP-2463290-A1 | THIENOOXAZEPINE DERIVATIVE | Takeda Pharmaceutical Company Limited (JP) | 2012-06-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120196848-A1 | THIENOOXAZEPINE DERIVATIVE | HTR2C, HTR2B, HTR2A | BRD4 550/4885CREBBP 758/4885EED 2484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.