Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 20/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2475977 | 1.00 | FOLH1 (0.74) | FOLH1 | |
| SCHEMBL4336030 | 0.90 | FOLH1 (0.72) | FOLH1 | |
| SCHEMBL19748291 | 0.87 | FOLH1 (0.69) | FOLH1 | |
| SCHEMBL19748972 | 0.86 | FOLH1 (0.68) | FOLH1 | |
| Iofolastat SCHEMBL2475975 | 0.85 | FOLH1 (1.00) | FOLH1 | |
| Iofolastat SCHEMBL9903616 | 0.85 | FOLH1 (1.00) | FOLH1 | |
| Iofolastat SCHEMBL20496027 | 0.85 | FOLH1 (1.00) | FOLH1 | |
| Iofolastat SCHEMBL18493678 | 0.85 | FOLH1 (1.00) | FOLH1 | |
| SCHEMBL19747822 | 0.85 | FOLH1 (0.70) | FOLH1 | |
| SCHEMBL4326624 | 0.84 | FOLH1 (0.91) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3057614-A1 | COMBINATION THERAPIES WITH PSMA LIGAND CONJUGATES | Psma Development Company, L.L.C. (US) | 2016-08-24 | — | — | EP | disclosed |
| WO-2015073896-A2 | BIOMARKERS FOR PSMA TARGETED THERAPY FOR PROSTATE CANCER | PSMA DEVELOPMENT COMPANY, LLC (US) | 2015-05-21 | — | — | WO | disclosed |
| WO-2015057250-A1 | COMBINATION THERAPIES WITH PSMA LIGAND CONJUGATES | PSMA DEVELOPMENT COMPANY, LLC (US) | 2015-04-23 | — | — | WO | disclosed |
| EP-2648766-A1 | PSMA-TARGETED DENDRIMERS | Molecular Insight Pharmaceuticals (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012078534-A1 | PSMA-TARGETED DENDRIMERS | MOLECULAR INSIGHT PHARMACEUTICALS (US) | 2012-06-14 | — | — | WO | disclosed |