Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.49 |
| ▸ | CDC25B | P30305 | 6/20 | 0.49 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.48 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.48 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.48 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.48 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | TACR2 | P21452 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2323060 | 1.00 | SLC6A2 (0.51) | SLC6A2PTPN1CDC25BSSTR1SSTR2 | |
| SCHEMBL7147911 | 1.00 | SLC6A2 (0.51) | SLC6A2PTPN1CDC25BSSTR1SSTR2 | |
| SCHEMBL7151103 | 1.00 | SLC6A2 (0.51) | SLC6A2PTPN1CDC25BSSTR1SSTR2 | |
| SCHEMBL4958359 | 1.00 | SLC6A2 (0.51) | SLC6A2PTPN1CDC25BSSTR1SSTR2 | |
| SCHEMBL1039870 | 1.00 | SLC6A2 (0.51) | SLC6A2PTPN1CDC25BSSTR1SSTR2 | |
| SCHEMBL23758909 | 1.00 | SLC6A2 (0.51) | SLC6A2PTPN1CDC25BSSTR1SSTR2 | |
| SCHEMBL10912453 | 1.00 | SLC6A2 (0.51) | SLC6A2PTPN1CDC25BSSTR1SSTR2 | |
| SCHEMBL18733412 | 1.00 | SLC6A2 (0.51) | SLC6A2PTPN1CDC25BSSTR1SSTR2 | |
| SCHEMBL6252622 | 1.00 | SLC6A2 (0.51) | SLC6A2PTPN1CDC25BSSTR1SSTR2 | |
| SCHEMBL30051250 | 1.00 | SLC6A2 (0.51) | SLC6A2PTPN1CDC25BSSTR1SSTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3259246-B1 | DERIVATIVES OF SOBETIROME | UNIV OREGON HEALTH & SCIENCE (US) | 2023-03-22 | — | — | EP | disclosed |
| CN-115286684-A | Conjugate of sugar and triptolide or derivatives thereof, and preparation method and application thereof | 福建医科大学 | 2022-11-04 | — | — | CN | disclosed |
| US-20210338849-A1 | COMPOUNDS AND COMPOSITIONS FOR THE DETECTION AND TREATMENT OF ALZHEIMER'S DISEASE AND RELATED DISORDERS | MASSACHUSETTS GEN HOSPITAL (US) | 2021-11-04 | — | — | US | disclosed |
| EP-3231804-B1 | COMPOUNDS AND COMPOSITIONS FOR THE DETECTION AND TREATMENT OF ALZHEIMER'S DISEASE AND RELATED DISORDERS | MASSACHUSETTS GEN HOSPITAL (US) | 2021-03-03 | — | — | EP | disclosed |
| US-10857247-B2 | Compounds and compositions for the detection and treatment of Alzheimer's disease and related disorders | THE GENERAL HOSPITAL CORPORATION (US) | 2020-12-08 | — | — | US | disclosed |
| US-20200181103-A1 | DERIVATIVES OF SOBETIROME | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2020-06-11 | — | — | US | disclosed |
| US-20200181103-A1 | DERIVATIVES OF SOBETIROME | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2020-06-11 | — | — | US | disclosed |
| US-10392356-B2 | Derivatives of sobetirome | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2019-08-27 | — | — | US | disclosed |
| US-10392356-B2 | Derivatives of sobetirome | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2019-08-27 | — | — | US | disclosed |
| US-20180057472-A1 | DERIVATIVES OF SOBETIROME | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2018-03-01 | — | — | US | disclosed |
| US-20090137499-A1 | BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-05-28 | — | — | US | disclosed |
| EP-2048150-A1 | BENZYL PHENYL GLUCOPYRANOSIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2009-04-15 | — | — | EP | disclosed |
| US-6562514-B1 | Stabilized vanadium electrolyte solutions for all-vanadium redox cells and batteries | PINNACLE VRB LIMITED (AU) | 2003-05-13 | — | — | US | disclosed |
| US-6468688-B2 | CHARGING, DISCHARGING EFFICIENCY; VANADIUM ELECTROLYTE | PINNACLE VRB LIMITED (AU) | 2002-10-22 | — | — | US | disclosed |
| US-20010028977-A1 | Charging, discharging efficiency; vanadium electrolyte | JD HOLDING INC. (KY) | 2001-10-11 | — | — | US | disclosed |
| US-6143443-A | ALL-VANADIUM REDOX BATTERY, COMPRISING THE STABILIZED ELECTROLYTE | PINNACLE ARB LIMITED (AU) | 2000-11-07 | — | — | US | disclosed |
| EP-0729648-A4 | STABILISED ELECTROLYTE SOLUTIONS, METHODS OF PREPARATION THEREOF AND REDOX CELLS AND BATTERIES CONTAINING STABILISED ELECTROLYTE SOLUTIONS | UNISEARCH LTD (AU) | 1997-01-02 | — | — | EP | disclosed |
| EP-0729648-A1 | STABILISED ELECTROLYTE SOLUTIONS, METHODS OF PREPARATION THEREOF AND REDOX CELLS AND BATTERIES CONTAINING STABILISED ELECTROLYTE SOLUTIONS | UNISEARCH LIMITED (AU) | 1996-09-04 | — | — | EP | disclosed |
| WO-1995012219-A1 | STABILISED ELECTROLYTE SOLUTIONS, METHODS OF PREPARATION THEREOF AND REDOX CELLS AND BATTERIES CONTAINING STABILISED ELECTROLYTE SOLUTIONS | UNISEARCH LIMITED (AU) | 1995-05-04 | — | — | WO | disclosed |
| US-5169636-A | Having a glycolipid membrane; resistant to uptake by the reticuloendothial system; efficient drug-delivery carriers | NIPPON FINE CHEMICAL CO., LTD. (JP) | 1992-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210338849-A1 | COMPOUNDS AND COMPOSITIONS FOR THE DETECTION AND TREATMENT OF ALZHEIMER'S DISEASE AND RELATED DISORDERS | APP, PSEN1, PSEN2 | SLC6A2 125/4885PTPN1 4606/4885CDC25B 4682/4885 |
| US-20090137499-A1 | BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE | SLC5A1, SLC5A2, SLC2A1 | SLC6A2 55/4885PTPN1 1591/4885CDC25B 4229/4885 |
| US-20200181103-A1 | DERIVATIVES OF SOBETIROME | SLC18A2, SLC6A2, SLC6A4 | SLC6A2 2/4885PTPN1 4221/4885CDC25B 4031/4885 |
| US-20180057472-A1 | DERIVATIVES OF SOBETIROME | SLC18A2, SLC6A2, SLC6A4 | SLC6A2 2/4885PTPN1 4221/4885CDC25B 4031/4885 |
| US-10857247-B2 | Compounds and compositions for the detection and treatment of Alzheimer's disease and related disorders | APP, PSEN1, PSEN2 | SLC6A2 125/4885PTPN1 4606/4885CDC25B 4682/4885 |
| US-10392356-B2 | Derivatives of sobetirome | SLC18A2, SLC6A2, SLC6A4 | SLC6A2 2/4885PTPN1 4221/4885CDC25B 4031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.