Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 13/20 | 0.62 |
| ▸ | PIK3CA | P42336 | 10/20 | 0.62 |
| ▸ | PIK3C2A | O00443 | 2/20 | 0.62 |
| ▸ | PIK3C2B | O00750 | 2/20 | 0.62 |
| ▸ | PIK3CD | O00329 | 9/20 | 0.61 |
| ▸ | ATM | Q13315 | 8/20 | 0.61 |
| ▸ | PIK3CB | P42338 | 6/20 | 0.61 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.61 |
| ▸ | ATR | Q13535 | 6/20 | 0.61 |
| ▸ | PRKDC | P78527 | 2/20 | 0.61 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.61 |
| ▸ | CSF1R | P07333 | 1/20 | 0.61 |
| ▸ | MET | P08581 | 1/20 | 0.61 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.61 |
| ▸ | LTK | P29376 | 1/20 | 0.61 |
| ▸ | CDK7 | P50613 | 1/20 | 0.61 |
| ▸ | NEK2 | P51955 | 1/20 | 0.61 |
| ▸ | JAK3 | P52333 | 1/20 | 0.61 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL993850 | 0.84 | MTOR (0.73) | MTORPIK3CAPIK3C2APIK3C2BPIK3CD | |
| SCHEMBL9905298 | 0.83 | MTOR (0.68) | MTORPIK3CAPIK3C2APIK3C2BPIK3CD | |
| SCHEMBL15747835 | 0.82 | MTOR (0.69) | MTORPIK3CAPIK3C2APIK3C2BPIK3CD | |
| SCHEMBL927006 | 0.82 | MTOR (0.71) | MTORPIK3CAPIK3C2APIK3C2BPIK3CD | |
| SCHEMBL9905317 | 0.81 | MTOR (0.66) | MTORPIK3CAPIK3C2APIK3C2BPIK3CD | |
| SCHEMBL9905096 | 0.81 | MTOR (0.66) | MTORPIK3CAPIK3C2APIK3C2BPIK3CD | |
| SCHEMBL928310 | 0.81 | MTOR (0.67) | MTORPIK3CAPIK3C2APIK3C2BPIK3CD | |
| SCHEMBL9905120 | 0.81 | MTOR (0.70) | MTORPIK3CAPIK3C2APIK3C2BPIK3CD | |
| SCHEMBL9905477 | 0.81 | MTOR (0.72) | MTORPIK3CAPIK3C2APIK3C2BPIK3CD | |
| SCHEMBL9905287 | 0.81 | MTOR (0.67) | MTORPIK3CAPIK3C2APIK3C2BPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130310374-A1 | Substituted Imidazoquinoline Derivatives | PIRAMAL ENTERPRISES LIMITED` (IN) | 2013-11-21 | — | — | US | claimed |
| US-20130310374-A1 | Substituted Imidazoquinoline Derivatives | PIRAMAL ENTERPRISES LIMITED` (IN) | 2013-11-21 | — | — | US | disclosed |
| EP-2648733-A1 | SUBSTITUTED IMIDAZOQUINOLINE DERIVATIVES | Piramal Enterprises Limited (IN) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077031-A1 | SUBSTITUTED IMIDAZOQUINOLINE DERIVATIVES | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2012-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130310374-A1 | Substituted Imidazoquinoline Derivatives | FLT4, CDK4, CDK2 | MTOR 220/4885PIK3CA 154/4885PIK3C2A 310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.