Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 16/20 | 0.54 |
| ▸ | PIK3CA | P42336 | 12/20 | 0.53 |
| ▸ | MTOR | P42345 | 13/20 | 0.52 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.52 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.52 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.52 |
| ▸ | ATR | Q13535 | 4/20 | 0.51 |
| ▸ | PRKDC | P78527 | 1/20 | 0.51 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.50 |
| ▸ | FECH | P22830 | 1/20 | 0.50 |
| ▸ | CLK1 | P49759 | 1/20 | 0.50 |
| ▸ | GSK3A | P49840 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | MELK | Q14680 | 1/20 | 0.50 |
| ▸ | MYLK3 | Q32MK0 | 1/20 | 0.50 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.50 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.50 |
| ▸ | TP53RK | Q96S44 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9902791 | 0.91 | MTOR (0.59) | ATMPIK3CAMTORPIK3CDPIK3CB | |
| SCHEMBL2068137 | 0.86 | ATM (0.55) | ATMPIK3CAMTORPIK3CDPIK3CB | |
| SCHEMBL9905208 | 0.86 | MTOR (0.58) | ATMPIK3CAMTORPIK3CDPIK3CB | |
| SCHEMBL9905147 | 0.85 | MTOR (0.64) | ATMPIK3CAMTORPIK3CDPIK3CB | |
| SCHEMBL9905307 | 0.83 | ATM (0.55) | ATMPIK3CAMTORPIK3CDPIK3CB | |
| SCHEMBL9905272 | 0.83 | PIK3CA (0.54) | ATMPIK3CAMTORPIK3CDPIK3CB | |
| SCHEMBL9905317 | 0.83 | MTOR (0.66) | ATMPIK3CAMTORPIK3CDPIK3CB | |
| SCHEMBL9905130 | 0.83 | MTOR (0.59) | ATMPIK3CAMTORPIK3CDPIK3CB | |
| SCHEMBL2067800 | 0.82 | MTOR (0.58) | ATMPIK3CAMTORPIK3CDPIK3CB | |
| SCHEMBL2068824 | 0.82 | PIK3CA (0.57) | ATMPIK3CAMTORPIK3CDPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2648733-A1 | SUBSTITUTED IMIDAZOQUINOLINE DERIVATIVES | Piramal Enterprises Limited (IN) | 2013-10-16 | — | — | EP | claimed |
| WO-2012077031-A1 | SUBSTITUTED IMIDAZOQUINOLINE DERIVATIVES | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2012-06-14 | — | — | WO | claimed |
| US-20130310374-A1 | Substituted Imidazoquinoline Derivatives | PIRAMAL ENTERPRISES LIMITED` (IN) | 2013-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130310374-A1 | Substituted Imidazoquinoline Derivatives | FLT4, CDK4, CDK2 | ATM 862/4885PIK3CA 154/4885MTOR 220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.