Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 20/20 | 0.49 |
| ▸ | CX3CR1 | P49238 | 14/20 | 0.49 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9902071 | 0.82 | CXCR2 (0.54) | CXCR2CX3CR1HTR1B | |
| SCHEMBL4063461 | 0.79 | CXCR2 (0.71) | CXCR2CX3CR1HTR1B | |
| SCHEMBL9905764 | 0.78 | CXCR2 (0.36) | CXCR2CX3CR1HTR1B | |
| SCHEMBL4061246 | 0.72 | CXCR2 (0.67) | CXCR2CX3CR1 | |
| SCHEMBL4061252 | 0.72 | CXCR2 (0.67) | CXCR2CX3CR1 | |
| SCHEMBL4058815 | 0.69 | CXCR2 (0.48) | CXCR2CX3CR1HTR1B | |
| SCHEMBL4059541 | 0.68 | CXCR2 (0.59) | CXCR2CX3CR1HTR1B | |
| SCHEMBL4059548 | 0.68 | CXCR2 (0.59) | CXCR2CX3CR1HTR1B | |
| SCHEMBL842644 | 0.68 | CXCR2 (0.71) | CXCR2CX3CR1HTR1B | |
| SCHEMBL841931 | 0.68 | CXCR2 (0.80) | CXCR2CX3CR1HTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2648754-A2 | METHODS OF INHIBITING METASTASIS FROM CANCER | Philadelphia Health and Education Corporation D/B/A (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012078633-A2 | METHODS OF INHIBITING METASTASIS FROM CANCER | PHILADELPHIA HEALTH AND EDUCATION CORPORATION, D/B/A DREXEL UNIVERSITY COLLEGE OF MEDICENE (US) | 2012-06-14 | — | — | WO | disclosed |