⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13559927 | 0.92 | — | — | |
| SCHEMBL14228190 | 0.90 | TSHR (0.30) | — | |
| SCHEMBL12039600 | 0.90 | TSHR (0.30) | — | |
| SCHEMBL14228189 | 0.90 | TSHR (0.30) | — | |
| SCHEMBL12709668 | 0.90 | TSHR (0.30) | — | |
| SCHEMBL10071074 | 0.82 | — | — | |
| SCHEMBL4955952 | 0.82 | TSHR (0.33) | — | |
| SCHEMBL13446990 | 0.79 | — | — | |
| SCHEMBL13415675 | 0.78 | — | — | |
| SCHEMBL9999533 | 0.76 | ANPEP (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198031-B2 | Using epidermal growth factor receptor complexes to diagnose and prognose health in cancer patients; drug screening | MONOGRAM BIOSCIENCES, INC. (US) | 2012-06-12 | — | — | US | disclosed |
| US-20080233602-A1 | Detecting and profiling molecular complexes | MONOGRAM BIOSCIENCES, INC. | 2008-09-25 | — | — | US | disclosed |
| US-20080132890-A1 | ELECTROSURGICAL APPARATUS AND METHODS FOR LAPAROSCOPY | ARTHROCARE CORPORATION (US) | 2008-06-05 | — | — | US | disclosed |