SCHEMBL9906995

SCHEMBL9906995

CP(C)(=O)Oc1cccc(OP(=O)(Oc2ccccc2)Oc2ccccc2)c1

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 1/20 0.46
CYP3A4 P08684 2/20 0.45
TSHR P16473 2/20 0.45
SRC P12931 1/20 0.45
L3MBTL1 Q9Y468 5/20 0.44
NPSR1 Q6W5P4 3/20 0.44
MAPK1 P28482 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
LMNA P02545 1/20 0.42
GAA P10253 1/20 0.42
ALDH1A1 P00352 1/20 0.41
HPGD P15428 5/20 0.41
KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL78015 0.90 SRC (0.54) HCRTR1CYP3A4TSHRSRCL3MBTL1
SCHEMBL25513746 0.90 SRC (0.54) HCRTR1CYP3A4TSHRSRCL3MBTL1
SCHEMBL7764936 0.88 HCRTR1 (0.46) HCRTR1SRCL3MBTL1TDP1LMNA
SCHEMBL676524 0.85 SRC (0.58) SRCL3MBTL1TDP1LMNAHPGD
SCHEMBL5381000 0.83 SRC (0.56) HCRTR1CYP3A4TSHRSRCL3MBTL1
SCHEMBL14051583 0.83 CYP3A4 (0.70) HCRTR1CYP3A4TSHRL3MBTL1NPSR1
SCHEMBL10013018 0.82 SRC (0.50) HCRTR1SRCL3MBTL1TDP1LMNA
Triphenyl Phosphate SCHEMBL483692 0.81 SRC (0.64) CYP3A4TSHRSRCL3MBTL1NPSR1
Triphenyl Phosphate SCHEMBL28761613 0.81 SRC (0.64) CYP3A4TSHRSRCL3MBTL1NPSR1
Triphenyl Phosphate SCHEMBL18116 0.81 SRC (0.64) CYP3A4TSHRSRCL3MBTL1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8623795-B2 Method for maintaining antiwear performance of turbine oils containing polymerized amine antioxidants and for improving the deposit formation resistance performance of turbine oils containing monomeric and/or polymeric antioxidants EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2014-01-07 US disclosed
US-20120142567-A1 METHOD FOR MAINTAINING ANTIWEAR PERFORMANCE OF TURBINE OILS CONTAINING POLYMERIZED AMINE ANTIOXIDANTS AND FOR IMPROVING THE DEPOSIT FORMATION RESISTANCE PERFORMANCE OF TURBINE OILS CONTAINING MONOMERIC AND/OR POLYMERIC ANTIOXIDANTS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2012-06-07 US disclosed
US-20120028861-A1 METHOD FOR IMPROVING THE DEPOSIT FORMATION RESISTANCE PERFORMANCE OF TURBINE OILS CONTAINING AMINE ANTIOXIDANTS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2012-02-02 US disclosed