SCHEMBL9908064

SCHEMBL9908064

C=CC(=O)OCCCCCCOc1ccc(C(=O)Oc2ccc(C)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.50
LMNA P02545 3/20 0.50
NFKB1 P19838 3/20 0.50
NFKB2 Q00653 3/20 0.50
RELA Q04206 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
HTT P42858 4/20 0.48
CYP3A4 P08684 2/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2D6 P10635 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
THRB P10828 1/20 0.48
TSHR P16473 2/20 0.47
ALDH1A1 P00352 2/20 0.47
MAPT P10636 4/20 0.47
KMT2A Q03164 2/20 0.47
GAA P10253 1/20 0.46
PRSS1 P07477 2/20 0.45
ACR P10323 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12891603 1.00 NPC1 (0.50) NPC1LMNANFKB1NFKB2RELA
SCHEMBL12769308 1.00 NPC1 (0.50) NPC1LMNANFKB1NFKB2RELA
SCHEMBL16379454 1.00 NPC1 (0.50) NPC1LMNANFKB1NFKB2RELA
SCHEMBL12768563 1.00 NPC1 (0.50) NPC1LMNANFKB1NFKB2RELA
SCHEMBL13149849 1.00 NPC1 (0.50) NPC1LMNANFKB1NFKB2RELA
SCHEMBL13109513 1.00 NPC1 (0.50) NPC1LMNANFKB1NFKB2RELA
SCHEMBL15214258 1.00 NPC1 (0.50) NPC1LMNANFKB1NFKB2RELA
SCHEMBL12304811 0.99 NPC1 (0.49) NPC1LMNANFKB1NFKB2RELA
SCHEMBL14484284 0.99 NPC1 (0.49) NPC1LMNANFKB1NFKB2RELA
SCHEMBL16379486 0.99 NPC1 (0.49) NPC1LMNANFKB1NFKB2RELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11788009-B2 Liquid-crystalline medium for use in a switching element MERCK PATENT GMBH (DE) 2023-10-17 US disclosed
US-11760931-B2 Liquid-crystalline medium for use in a switching element MERCK PATENT GMBH (DE) 2023-09-19 US disclosed
EP-3343285-A1 LIQUID CRYSTAL CELL LG Chem, Ltd. (KR) 2018-07-04 EP disclosed
US-20170371211-A1 MULTIPLE ALIGNMENT METHOD IN LIQUID CRYSTALLINE MEDIUM CONSIGLIO NAZIONALE DELLE RICERCHE - CNR (IT) 2017-12-28 US disclosed
US-9663718-B2 Method of preparing a birefringent polymer film MERCK PATENT GMBH (DE) 2017-05-30 US disclosed
US-9617476-B2 Liquid crystal composition HUIZHOU FORYOU OPTICAL TECHNOLOGY CO., LTD. (CN) 2017-04-11 US disclosed
US-20170038643-A1 DISPLAY PANEL AND MANUFACTURING METHOD THEREOF AU OPTRONICS CORPORATION (TW) 2017-02-09 US disclosed
US-20150344781-A1 LIQUID CRYSTAL COMPOSITION HUIZHOU FORYOU OPTICAL TECHNOLOGY CO., LTD. (CN) 2015-12-03 US disclosed
US-20150315012-A1 LIGHT DRIVEN LIQUID CRYSTAL ELASTOMER ACTUATOR ISTITUTO ITALIANO DI TECNOLOGIA (IT) 2015-11-05 US disclosed
US-8518299-B2 Dichroic guest-host polarizer comprising an oriented polymer film SUMITOMO CHEMICAL CO., LTD. (JP) 2013-08-27 US disclosed
US-20090040443-A1 METHOD OF PRODUCING A LIQUID CRYSTAL PANEL, LIQUID CRYSTAL PANEL, AND IMAGE DISPLAY APPARATUS NITTO DENKO CORPORATION (JP) 2009-02-12 US disclosed
US-20090040443-A1 METHOD OF PRODUCING A LIQUID CRYSTAL PANEL, LIQUID CRYSTAL PANEL, AND IMAGE DISPLAY APPARATUS NITTO DENKO CORPORATION (JP) 2009-02-12 US disclosed
US-7344762-B2 Printable liquid crystal material MERCK PATENT GMBH (DE) 2008-03-18 US disclosed
US-7288297-B2 Optical compensation plate, polarizing plate using the same and image display apparatus using the same NITTO DENKO CORPORATION (JP) 2007-10-30 US disclosed
US-7288297-B2 Optical compensation plate, polarizing plate using the same and image display apparatus using the same NITTO DENKO CORPORATION (JP) 2007-10-30 US disclosed
US-7270855-B2 Optical film, method for manufacturing the same, and phase difference film and polarizing plate using the same NITTO DENKO CORPORATION (JP) 2007-09-18 US disclosed
US-7270855-B2 Optical film, method for manufacturing the same, and phase difference film and polarizing plate using the same NITTO DENKO CORPORATION (JP) 2007-09-18 US disclosed
US-7235283-B2 Optical compensation plate and deflecting plate using the same NITTO DENKO CORPORATION (JP) 2007-06-26 US disclosed
US-7235283-B2 Optical compensation plate and deflecting plate using the same NITTO DENKO CORPORATION (JP) 2007-06-26 US disclosed
US-7170575-B2 Homeotropically aligned liquid crystal layer and process for the homeotropic alignment of liquid crystals on plastic substrates MERCK PATENT GMBH (DE) 2007-01-30 US disclosed