Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 2/20 | 0.59 |
| ▸ | TYMP | P19971 | 4/20 | 0.49 |
| ▸ | PYGM | P11217 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9908677 | 1.00 | TK2 (0.59) | TK2TYMPPYGMALDH1A1LMNA | |
| SCHEMBL773378 | 1.00 | TK2 (0.59) | TK2TYMPPYGMALDH1A1LMNA | |
| SCHEMBL767907 | 1.00 | TK2 (0.59) | TK2TYMPPYGMALDH1A1LMNA | |
| SCHEMBL774127 | 1.00 | TK2 (0.59) | TK2TYMPPYGMALDH1A1LMNA | |
| SCHEMBL767995 | 1.00 | TK2 (0.59) | TK2TYMPPYGMALDH1A1LMNA | |
| SCHEMBL767896 | 0.92 | TK2 (0.52) | TK2TYMPALDH1A1LMNAALB | |
| SCHEMBL9908676 | 0.92 | TK2 (0.52) | TK2TYMPALDH1A1LMNAALB | |
| SCHEMBL767975 | 0.92 | TK2 (0.52) | TK2TYMPALDH1A1LMNAALB | |
| SCHEMBL9908669 | 0.92 | TK2 (0.52) | TK2TYMPALDH1A1LMNAALB | |
| SCHEMBL767989 | 0.92 | TK2 (0.52) | TK2TYMPALDH1A1LMNAALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9512164-B2 | Oligonucleotide end caps | ALNYLAM PHARMACEUTICALS, INC. (US) | 2016-12-06 | — | — | US | disclosed |
| US-20120142101-A1 | OLIGONUCLEOTIDE END CAPS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2012-06-07 | — | — | US | disclosed |