SCHEMBL9909394

CCC(=O)[C@@H]1CSCCCC(=O)N[C@@H](CCCCNC(C)(C)C)C(=O)N[C@H]2CSSC[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC2=O)C(=O)N[C@@H](Cc2ccccc2)C(=O)N1

nearest known ligand 0.56

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	MC4R	P32245	9/20	0.56

▸	MC5R	P33032	9/20	0.56

▸	MC3R	P41968	9/20	0.56

▸	MC1R	Q01726	9/20	0.56

▸	TSLP	Q969D9	9/20	0.51

▸	CTSG	P08311	1/20	0.49

▸	ITGB3	P05106	1/20	0.48

▸	ITGB1	P05556	1/20	0.48

▸	ITGAV	P06756	1/20	0.48

▸	ITGA5	P08648	1/20	0.48

▸	ITGB5	P18084	1/20	0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9909387	0.95	MC4R (0.57)	MC4RMC5RMC3RMC1RTSLP
SCHEMBL9909398	0.88	MC4R (0.59)	MC4RMC5RMC3RMC1RTSLP
SCHEMBL11933446	0.88	MC4R (0.56)	MC4RMC5RMC3RMC1RTSLP
SCHEMBL13485887	0.88	MC4R (0.57)	MC4RMC5RMC3RMC1RTSLP
SCHEMBL13234351	0.87	MC4R (0.53)	MC4RMC5RMC3RMC1RTSLP
SCHEMBL9908285	0.87	MC4R (0.54)	MC4RMC5RMC3RMC1RTSLP
SCHEMBL15623628	0.87	MC4R (0.57)	MC4RMC5RMC3RMC1RTSLP
SCHEMBL9908254	0.86	MC4R (0.56)	MC4RMC5RMC3RMC1RTSLP
SCHEMBL12307752	0.84	MC4R (0.53)	MC4RMC5RMC3RMC1RTSLP
SCHEMBL12918029	0.83	MC4R (0.57)	MC4RMC5RMC3RMC1RTSLP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-8197793-B2	Methods of radiofluorination of biologically active vectors	GE HEALTHCARE AS (NO)	2012-06-12	—	—	US	disclosed