Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 2/20 | 0.59 |
| ▸ | TYMP | P19971 | 4/20 | 0.52 |
| ▸ | PYGM | P11217 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL774129 | 0.89 | TK2 (0.63) | TK2TYMPPYGMALDH1A1LMNA | |
| SCHEMBL773813 | 0.88 | TK2 (0.61) | TK2TYMPPYGMALDH1A1LMNA | |
| SCHEMBL8163247 | 0.87 | TK2 (0.60) | TK2TYMPPYGMALDH1A1LMNA | |
| SCHEMBL773772 | 0.87 | TK2 (0.60) | TK2TYMPPYGMALDH1A1LMNA | |
| SCHEMBL312987 | 0.87 | TK2 (0.60) | TK2TYMPPYGMALDH1A1LMNA | |
| SCHEMBL773054 | 0.87 | TK2 (0.60) | TK2TYMPPYGMALDH1A1LMNA | |
| SCHEMBL767995 | 0.86 | TK2 (0.59) | TK2TYMPPYGMALDH1A1LMNA | |
| SCHEMBL9908677 | 0.86 | TK2 (0.59) | TK2TYMPPYGMALDH1A1LMNA | |
| SCHEMBL767907 | 0.86 | TK2 (0.59) | TK2TYMPPYGMALDH1A1LMNA | |
| SCHEMBL774127 | 0.86 | TK2 (0.59) | TK2TYMPPYGMALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142101-A1 | OLIGONUCLEOTIDE END CAPS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2012-06-07 | — | — | US | disclosed |