Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 20/20 | 0.81 |
| ▸ | PPARG | P37231 | 18/20 | 0.81 |
| ▸ | PPARD | Q03181 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20235204 | 0.92 | PPARA (0.80) | PPARAPPARGPPARD | |
| SCHEMBL13048592 | 0.92 | PPARA (0.80) | PPARAPPARGPPARD | |
| SCHEMBL9910100 | 0.91 | PPARA (0.80) | PPARAPPARGPPARD | |
| SCHEMBL13949675 | 0.90 | PPARA (0.82) | PPARAPPARGPPARD | |
| SCHEMBL4685996 | 0.90 | PPARA (1.00) | PPARAPPARGPPARD | |
| SCHEMBL820622 | 0.90 | PPARA (1.00) | PPARAPPARGPPARD | |
| SCHEMBL821108 | 0.89 | PPARA (0.84) | PPARAPPARGPPARD | |
| SCHEMBL20235209 | 0.89 | PPARA (0.82) | PPARAPPARGPPARD | |
| SCHEMBL9910267 | 0.88 | PPARA (0.68) | PPARAPPARGPPARD | |
| SCHEMBL12601491 | 0.87 | PPARA (0.67) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012074980-A2 | METHODS OF TREATING OR PREVENTING AUTOIMMUNE DISORDERS AND LIVER DISORDERS USING INDANE ACETIC ACID DERIVATIVES | DARA BIOSCIENCES, INC. (US) | 2012-06-07 | — | — | WO | disclosed |
| US-7476742-B2 | Indane acetic acid derivatives and their use as pharmaceutical agents | BAYER PHARMACEUTICALS CORPORATION (US) | 2009-01-13 | — | — | US | disclosed |