Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | GLS | O94925 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL888690 | 1.00 | MEN1 (0.44) | MEN1KMT2ASMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL13049150 | 0.87 | HSD17B10 (0.43) | MEN1KMT2AHSD17B10POLBKDM4E | |
| SCHEMBL10140615 | 0.86 | HPGD (0.43) | MEN1KMT2AMTNR1AMTNR1BHSD17B10 | |
| SCHEMBL5746466 | 0.85 | GAA (0.46) | MEN1KMT2ASMN1; SMN2HSD17B10POLB | |
| SCHEMBL10076918 | 0.83 | MEN1 (0.47) | MEN1KMT2ASMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL890060 | 0.82 | TACR3 (0.48) | KMT2AMTNR1AMTNR1BHSD17B10SRC | |
| SCHEMBL4250144 | 0.82 | SRC (0.52) | KMT2AMTNR1AMTNR1BSRCPOLB | |
| SCHEMBL3376625 | 0.82 | SRC (0.52) | KMT2AMTNR1AMTNR1BSRCPOLB | |
| SCHEMBL627377 | 0.82 | SRC (0.52) | KMT2AMTNR1AMTNR1BSRCPOLB | |
| SCHEMBL5744468 | 0.82 | TACR3 (0.48) | KMT2AMTNR1AMTNR1BHSD17B10SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198458-B2 | Non-nucleoside reverse transcriptase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-12 | — | — | US | disclosed |
| US-7517998-B2 | Benzothiazole or benzothiazine derivative of dipyrido(2,3;b:2',3'-e) diazepin-6-one; viricide against human t-cell leukemia/lymphoma virus | BOEHRINGER INGELHEIM INTERNATIONAL GMBH | 2009-04-14 | — | — | US | disclosed |
| US-7517998-B2 | Benzothiazole or benzothiazine derivative of dipyrido(2,3;b:2',3'-e) diazepin-6-one; viricide against human t-cell leukemia/lymphoma virus | BOEHRINGER INGELHEIM INTERNATIONAL GMBH | 2009-04-14 | — | — | US | disclosed |