Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4096396 | 0.82 | HSP90AA1 (0.71) | HSP90AA1 | |
| SCHEMBL13927810 | 0.81 | HSP90AA1 (0.58) | HSP90AA1 | |
| SCHEMBL4086559 | 0.68 | HSP90AA1 (0.71) | HSP90AA1 | |
| SCHEMBL4092059 | 0.65 | HSP90AA1 (0.78) | HSP90AA1 | |
| SCHEMBL4096885 | 0.64 | HSP90AA1 (0.80) | HSP90AA1 | |
| SCHEMBL4090902 | 0.64 | HSP90AA1 (0.91) | HSP90AA1 | |
| SCHEMBL4096738 | 0.63 | HSP90AA1 (0.69) | HSP90AA1 | |
| SCHEMBL4086348 | 0.63 | HSP90AA1 (1.00) | HSP90AA1 | |
| SCHEMBL4096975 | 0.63 | HSP90AA1 (0.89) | HSP90AA1 | |
| SCHEMBL10577059 | 0.63 | KMT2A (0.47) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8193351-B2 | HSP90 inhibitor | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2012-06-05 | — | — | US | disclosed |
| US-8193351-B2 | HSP90 inhibitor | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2012-06-05 | — | — | US | disclosed |
| US-20090247524-A1 | HSP90 Inhibitor | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-10-01 | — | — | US | disclosed |
| US-20090247524-A1 | HSP90 Inhibitor | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247524-A1 | HSP90 Inhibitor | HSP90AB1, HSP90B1, HSP90AA1 | HSP90AA1 3/4885MAPT 868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.