Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 15/20 | 0.51 |
| ▸ | KDM1A | O60341 | 14/20 | 0.51 |
| ▸ | RCOR1 | Q9UKL0 | 13/20 | 0.51 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.42 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | KMT5A | Q9NQR1 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9911783 | 1.00 | EHMT2 (0.51) | EHMT2KDM1ARCOR1DNMT3AHDAC1 | |
| SCHEMBL9911784 | 1.00 | EHMT2 (0.51) | EHMT2KDM1ARCOR1DNMT3AHDAC1 | |
| SCHEMBL9911782 | 0.97 | EHMT2 (0.49) | EHMT2KDM1ARCOR1DNMT3AHDAC1 | |
| SCHEMBL4202905 | 0.92 | EHMT2 (0.49) | EHMT2KDM1ARCOR1DNMT3AHDAC1 | |
| SCHEMBL4207153 | 0.90 | EHMT2 (0.48) | EHMT2KDM1ARCOR1DNMT3AHDAC1 | |
| SCHEMBL9911787 | 0.88 | EHMT2 (0.59) | EHMT2KDM1ARCOR1DNMT3AEHMT1 | |
| SCHEMBL1427813 | 0.87 | EHMT2 (0.51) | EHMT2KDM1ARCOR1DNMT3AEZH2 | |
| SCHEMBL1428467 | 0.86 | EHMT2 (0.49) | EHMT2KDM1ARCOR1DNMT3AEZH2 | |
| SCHEMBL9911788 | 0.85 | EHMT2 (0.51) | EHMT2KDM1ARCOR1HDAC1HDAC6 | |
| SCHEMBL9911839 | 0.84 | EHMT2 (0.52) | EHMT2KDM1ARCOR1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8193203-B2 | Bicyclic compounds having activity at the CXCR4 receptor | ALLERGAN, INC. (US) | 2012-06-05 | — | — | US | disclosed |
| US-8193203-B2 | Bicyclic compounds having activity at the CXCR4 receptor | ALLERGAN, INC. (US) | 2012-06-05 | — | — | US | disclosed |
| US-20090312305-A1 | BICYCLIC COMPOUNDS HAVING ACTIVITY AT THE CXCR4 RECEPTOR | ALLERGAN, INC. (US) | 2009-12-17 | — | — | US | disclosed |
| US-20090312305-A1 | BICYCLIC COMPOUNDS HAVING ACTIVITY AT THE CXCR4 RECEPTOR | ALLERGAN, INC. (US) | 2009-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312305-A1 | BICYCLIC COMPOUNDS HAVING ACTIVITY AT THE CXCR4 RECEPTOR | CXCR4, CXCR2, CXCL12 | EHMT2 4669/4885KDM1A 4804/4885RCOR1 3069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.