Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | NEU1 | Q99519 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12731824 | 0.84 | MEN1 (0.49) | MEN1LMNACYP3A4KMT2ANEU1 | |
| SCHEMBL15259238 | 0.84 | MEN1 (0.62) | MEN1LMNACYP3A4KMT2ANEU1 | |
| SCHEMBL8522763 | 0.84 | MEN1 (0.62) | MEN1LMNACYP3A4KMT2ANEU1 | |
| SCHEMBL2828107 | 0.84 | MEN1 (0.62) | MEN1LMNACYP3A4KMT2ANEU1 | |
| SCHEMBL12872270 | 0.84 | MEN1 (0.62) | MEN1LMNACYP3A4KMT2ANEU1 | |
| SCHEMBL15374789 | 0.83 | MEN1 (0.61) | MEN1LMNACYP3A4KMT2ANEU1 | |
| SCHEMBL125997 | 0.83 | MEN1 (0.61) | MEN1LMNACYP3A4KMT2ANEU1 | |
| SCHEMBL12820864 | 0.81 | MEN1 (0.57) | MEN1LMNACYP3A4KMT2ANEU1 | |
| SCHEMBL12708803 | 0.80 | MEN1 (0.58) | MEN1LMNACYP3A4KMT2ANEU1 | |
| SCHEMBL15986522 | 0.79 | MEN1 (0.57) | MEN1LMNACYP3A4KMT2ANEU1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012050645-A9 | PATHOGEN DETECTION | PURDUE RESEARCH FOUNDATION (US) | 2012-06-07 | — | — | WO | disclosed |
| WO-2012050645-A2 | PATHOGEN DETECTION | PURDUE RESEARCH FOUNDATION (US) | 2012-04-19 | — | — | WO | disclosed |