⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16283952 | 0.76 | — | — | |
| SCHEMBL18573498 | 0.74 | — | — | |
| SCHEMBL14469598 | 0.74 | — | — | |
| SCHEMBL15213213 | 0.74 | — | — | |
| SCHEMBL13562497 | 0.74 | — | — | |
| SCHEMBL4568011 | 0.71 | — | — | |
| SCHEMBL18571111 | 0.70 | — | — | |
| SCHEMBL19119130 | 0.70 | — | — | |
| SCHEMBL12812914 | 0.69 | — | — | |
| SCHEMBL17451024 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |
| WO-2022221739-A1 | SMALL MOLECULE INHIBITORS OF KRAS G12D MUTANT | MERCK SHARP & DOHME CORP. (US) | 2022-10-20 | — | — | WO | disclosed |
| EP-1939204-B3 | FUSED HETEROCYCLIC DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND MEDICINAL USE THEREOF | KISSEI PHARMACEUTICAL (JP) | 2022-08-24 | — | — | EP | disclosed |
| EP-3613743-A1 | PROCESSES FOR THE PREPARATION OF 1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE DERIVATIVES | Intellikine, LLC (US) | 2020-02-26 | — | — | EP | disclosed |
| EP-2619184-B1 | DEUBIQUITINASE INHIBITORS AND METHODS FOR USE OF THE SAME | UNIV MICHIGAN REGENTS (US) | 2018-05-23 | — | — | EP | disclosed |
| EP-2490279-B1 | AROMATIC POLYMER ION EXCHANGE MEMBRANE AND ITS COMPLEX MEMBRANE AND ITS APPLICATION FOR ACIDIC ELECTROLYTE FLOW ENERGY STORAGE BATTERY | DALIAN INST CHEMICAL PHYSICS CAS (CN) | 2017-08-02 | — | — | EP | disclosed |
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |
| EP-2573073-A1 | Pyrazoloquinolinone derivatives, preparation thereof and therapeutic use thereof | SANOFI (FR) | 2013-03-27 | — | — | EP | disclosed |
| EP-2174934-B1 | OXOPYRAZINE DERIVATIVE AND HERBICIDE | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2012-06-06 | — | — | EP | disclosed |
| EP-2378585-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT MATERIAL AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME | Idemitsu Kosan Co., Ltd. (JP) | 2011-10-19 | — | — | EP | disclosed |
| EP-2221897-A1 | ORGANIC EL ELEMENT AND SOLUTION CONTAINING ORGANIC EL MATERIAL | Idemitsu Kosan Co., Ltd. (JP) | 2010-08-25 | — | — | EP | disclosed |
| EP-2221896-A1 | ORGANIC EL ELEMENT | Idemitsu Kosan Co., Ltd. (JP) | 2010-08-25 | — | — | EP | disclosed |