Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 20/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13887687 | 0.92 | PTGDR (0.68) | PTGDR | |
| SCHEMBL4508612 | 0.91 | PTGDR (0.76) | PTGDR | |
| SCHEMBL4499718 | 0.88 | PTGDR (0.67) | PTGDR | |
| SCHEMBL9912246 | 0.85 | PTGDR (0.67) | PTGDR | |
| SCHEMBL9912245 | 0.83 | PTGDR (0.71) | PTGDR | |
| SCHEMBL4491374 | 0.82 | PTGDR (0.73) | PTGDR | |
| SCHEMBL4499612 | 0.82 | PTGDR (0.76) | PTGDR | |
| SCHEMBL4496656 | 0.81 | PTGDR (0.71) | PTGDR | |
| SCHEMBL4489710 | 0.81 | PTGDR (1.00) | PTGDR | |
| SCHEMBL4500130 | 0.81 | PTGDR (0.87) | PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8193183-B2 | 2,6-substituted-4-monosubstitutedamino-pyrimidine as prostaglandin D2 receptor antagonists | AVENTIS PHARMACEUTICALS INC. (US) | 2012-06-05 | — | — | US | disclosed |
| US-7517889-B2 | 2,6-substituted-4-monosubstitutedamino-pyrimidine as prostaglandin D2 receptor antagonists | AVENTIS PHARMACEUTICALS, INC. (US) | 2009-04-14 | — | — | US | disclosed |