Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 20/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4501173 | 0.90 | PTGDR (0.71) | PTGDR | |
| SCHEMBL10475983 | 0.89 | PTGDR (0.70) | PTGDR | |
| SCHEMBL10475984 | 0.89 | PTGDR (0.70) | PTGDR | |
| SCHEMBL4494625 | 0.76 | PTGDR (0.66) | PTGDR | |
| SCHEMBL4506118 | 0.76 | PTGDR (0.72) | PTGDR | |
| SCHEMBL9912272 | 0.76 | PTGDR (0.60) | PTGDR | |
| Hydrochloric Acid SCHEMBL4492644 | 0.76 | PTGDR (0.65) | PTGDR | |
| SCHEMBL4496881 | 0.75 | PTGDR (0.68) | PTGDR | |
| SCHEMBL9911104 | 0.75 | PTGDR (0.68) | PTGDR | |
| SCHEMBL4505164 | 0.74 | PTGDR (0.76) | PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8193183-B2 | 2,6-substituted-4-monosubstitutedamino-pyrimidine as prostaglandin D2 receptor antagonists | AVENTIS PHARMACEUTICALS INC. (US) | 2012-06-05 | — | — | US | disclosed |
| US-7517889-B2 | 2,6-substituted-4-monosubstitutedamino-pyrimidine as prostaglandin D2 receptor antagonists | AVENTIS PHARMACEUTICALS, INC. (US) | 2009-04-14 | — | — | US | disclosed |