Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.74 |
| ▸ | LMNA | P02545 | 6/20 | 0.74 |
| ▸ | THRB | P10828 | 5/20 | 0.74 |
| ▸ | GAA | P10253 | 5/20 | 0.74 |
| ▸ | HTT | P42858 | 4/20 | 0.74 |
| ▸ | HPGD | P15428 | 3/20 | 0.74 |
| ▸ | RECQL | P46063 | 3/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.74 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.74 |
| ▸ | POLB | P06746 | 2/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.74 |
| ▸ | PKM | P14618 | 3/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13104752 | 0.93 | MAPT (0.62) | MAPTKDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL20757413 | 0.91 | MAPT (0.79) | MAPTKDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL12588713 | 0.91 | MAPT (0.68) | MAPTKDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9912635 | 0.91 | MAPT (0.70) | MAPTKDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL13104779 | 0.90 | MAPT (0.64) | MAPTKDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL13104775 | 0.90 | MAPT (0.67) | MAPTKDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL14444985 | 0.90 | MAPT (0.67) | MAPTKDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL13104745 | 0.90 | MAPT (0.67) | MAPTKDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL13104780 | 0.90 | MAPT (0.69) | MAPTKDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL13578501 | 0.90 | MAPT (0.74) | MAPTKDM4ESMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8865029-B2 | Photochromic polymer and composition comprising photochromic polymer | Vivimed Labs Europe Ltd. (GB) | 2014-10-21 | — | — | US | disclosed |
| US-8865029-B2 | Photochromic polymer and composition comprising photochromic polymer | Vivimed Labs Europe Ltd. (GB) | 2014-10-21 | — | — | US | disclosed |
| EP-2294114-B1 | PHOTOCHROMIC POLYMER AND COMPOSITION COMPRISING PHOTOCHROMIC POLYMER | ADVANCED POLYMERIK PTY LTD (AU) | 2012-08-15 | — | — | EP | disclosed |
| EP-1560893-B1 | PHOTOCHROMIC COMPOSITIONS AND LIGHT TRANSMISSIBLE ARTICLES | ADVANCED POLYMERIK PTY LTD (AU) | 2012-06-06 | — | — | EP | disclosed |
| US-20110147681-A1 | Photochromic Polymer and Composition Comprising Photochromic Polymer | ADVANCED POLYMERIK PTY LTD (AU) | 2011-06-23 | — | — | US | disclosed |
| US-20110147681-A1 | Photochromic Polymer and Composition Comprising Photochromic Polymer | ADVANCED POLYMERIK PTY LTD (AU) | 2011-06-23 | — | — | US | disclosed |
| US-7807075-B2 | Photochromic compositions and light transmissible articles | ADVANCED POLYMERIK PTY LTD (AU) | 2010-10-05 | — | — | US | disclosed |
| US-7807075-B2 | Photochromic compositions and light transmissible articles | ADVANCED POLYMERIK PTY LTD (AU) | 2010-10-05 | — | — | US | disclosed |
| WO-2009121148-A1 | DYE COMPRISING FUNCTIONAL SUBSTITUENT | ADVANCED POLYMERIK PTY LTD (AU) | 2009-10-08 | — | — | WO | disclosed |
| US-20090093601-A1 | Photochromic Compounds Comprising Polymeric Substituents And Methods For Preparation And Use Thereof | POLYMERS AUSTRALIA PTY LIMITED (AU) | 2009-04-09 | — | — | US | disclosed |
| US-20080006798-A1 | Photochromic Compositions and Light Transmissible Articles | JAMES ROBINSON SPECIALITY INGREDIENTS LTD (GB) | 2008-01-10 | — | — | US | disclosed |
| US-20080006798-A1 | Photochromic Compositions and Light Transmissible Articles | JAMES ROBINSON SPECIALITY INGREDIENTS LTD (GB) | 2008-01-10 | — | — | US | disclosed |
| US-7247262-B2 | Photochromic compositions and light transmissible articles | POLYMERS AUSTRALIA PTY LTD. (AU) | 2007-07-24 | — | — | US | disclosed |
| US-7247262-B2 | Photochromic compositions and light transmissible articles | POLYMERS AUSTRALIA PTY LTD. (AU) | 2007-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110147681-A1 | Photochromic Polymer and Composition Comprising Photochromic Polymer | SMCHD1, PCNA, PARG | MAPT 94/4885KDM4E 2245/4885SMN1; SMN2 1660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.