Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 20/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9912753 | 0.94 | BRAF (0.80) | BRAF | |
| SCHEMBL9912795 | 0.94 | BRAF (0.79) | BRAF | |
| SCHEMBL9912759 | 0.92 | BRAF (0.81) | BRAF | |
| SCHEMBL9912783 | 0.88 | BRAF (0.80) | BRAF | |
| SCHEMBL9912775 | 0.87 | BRAF (0.81) | BRAF | |
| SCHEMBL9912747 | 0.87 | BRAF (0.79) | BRAF | |
| SCHEMBL14964670 | 0.87 | BRAF (0.70) | BRAF | |
| SCHEMBL15300284 | 0.86 | BRAF (0.62) | BRAF | |
| SCHEMBL9912781 | 0.86 | BRAF (0.80) | BRAF | |
| SCHEMBL9912803 | 0.86 | BRAF (0.80) | BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9216981-B2 | Purinylpyridinylamino-2,4-difluorophenyl sulfonamide derivative, pharmaceutically acceptable salt thereof, preparation method thereof, and pharmaceutical composition with inhibitory activity against Raf kinase, containing same as active ingredient | MEDPACTO, INC. (KR) | 2015-12-22 | — | — | US | disclosed |
| WO-2012074249-A2 | NOVEL PURINYLPYRIDINYLAMINO-2,4-DIFLUOROPHENYL SULFONAMIDE DERIVATIVE, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION WITH INHIBITORY ACTIVITY AGAINST RAF KINASE, CONTAINING SAME AS ACTIVE INGREDIENT | 주식회사 유아이 (KR) | 2012-06-07 | — | — | WO | disclosed |