⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23398 | 0.70 | — | — | |
| SCHEMBL23397 | 0.70 | — | — | |
| Bicarbonate SCHEMBL796513 | 0.70 | — | — | |
| SCHEMBL243530 | 0.70 | — | — | |
| Bicarbonate SCHEMBL3917413 | 0.70 | — | — | |
| Bicarbonate SCHEMBL194552 | 0.70 | — | — | |
| Bicarbonate SCHEMBL16673755 | 0.70 | CA1 (0.50) | — | |
| SCHEMBL18740 | 0.70 | — | — | |
| Bicarbonate SCHEMBL8827978 | 0.70 | TSHR (0.60) | — | |
| Bicarbonate SCHEMBL29012214 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150272929-A1 | ORGANIC COMPOUNDS | UMBRICHT DANIEL (CH) | 2015-10-01 | — | — | US | disclosed |
| US-20140194423-A1 | COMBINATION PRODUCTS | GOMEZ-MANCILLA BALTAZAR (CH) | 2014-07-10 | — | — | US | disclosed |
| US-20140187600-A1 | USE OF METABOTROPIC GLUTAMATE RECEPTORS | GLATTHAR RALF (DE) | 2014-07-03 | — | — | US | disclosed |
| US-8703809-B2 | Combination products | NOVARTIS AG (CH) | 2014-04-22 | — | — | US | disclosed |
| US-8610998-B2 | Coloured organic electrophoretic particles | BASF SE (DE) | 2013-12-17 | — | — | US | disclosed |
| US-20120309742-A1 | USE OF METABOTROPIC GLUTAMATE RECEPTORS | GLATTHAR RALF (DE) | 2012-12-06 | — | — | US | disclosed |
| US-20120122878-A1 | COMBINATION PRODUCTS | NOVARTIS AG (CH) | 2012-05-17 | — | — | US | disclosed |
| US-20110216392-A1 | Coloured organic electrophoretic particles | BASF SE (DE) | 2011-09-08 | — | — | US | disclosed |
| EP-2320892-A2 | COMBINATION PRODUCTS | Novartis AG (CH) | 2011-05-18 | — | — | EP | disclosed |
| EP-2272509-A1 | New Uses of metabotropic glutamate receptors | Novartis AG (CH) | 2011-01-12 | — | — | EP | disclosed |
| US-7696379-B2 | Acetylene derivatives | NOVARTIS AG (CH) | 2010-04-13 | — | — | US | disclosed |
| US-20100041641-A1 | USES OF METABOTROPIC GLUTAMATE RECEPTORS | RALF GLATTHAR | 2010-02-18 | — | — | US | disclosed |
| WO-2010000763-A2 | COMBINATION PRODUCTS | NOVARTIS AG (CH) | 2010-01-07 | — | — | WO | disclosed |
| EP-2046896-A2 | COLOURED ORGANIC ELECTROPHORETIC PARTICLES | Ciba Holding Inc. (CH) | 2009-04-15 | — | — | EP | disclosed |
| US-20080269250-A1 | Pyrrolidine and Piperidine Acetylene Derivatives for Use as Mglur5 Antagonists | NOVARTIS AG (CH) | 2008-10-30 | — | — | US | disclosed |
| US-20080214673-A1 | Acetylene Derivatives | NOVARTIS AG (CH) | 2008-09-04 | — | — | US | disclosed |
| EP-1877365-A1 | ACETYLENE DERIVATIVES | Novartis AG (CH) | 2008-01-16 | — | — | EP | disclosed |
| WO-2008003604-A2 | COLOURED ORGANIC ELECTROPHORETIC PARTICLES | CIBA HOLDING INC. (CH) | 2008-01-10 | — | — | WO | disclosed |
| WO-2007107471-A2 | ANTHRAQUINONE DYE DERIVATIVES AND THEIR USE | CLARIANT INTERNATIONAL LTD (CH) | 2007-09-27 | — | — | WO | disclosed |
| WO-2006114262-A1 | ACETYLENE DERIVATIVES | NOVARTIS AG (CH) | 2006-11-02 | — | — | WO | disclosed |