Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 15/20 | 0.91 |
| ▸ | S1PR1 | P21453 | 14/20 | 0.91 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.68 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.68 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3047513 | 0.95 | S1PR5 (1.00) | S1PR5S1PR1S1PR3S1PR4TNK2 | |
| SCHEMBL13215741 | 0.86 | S1PR5 (0.91) | S1PR5S1PR1S1PR3S1PR4 | |
| SCHEMBL16695243 | 0.84 | S1PR5 (0.82) | S1PR5S1PR1S1PR3S1PR4 | |
| SCHEMBL3027647 | 0.84 | S1PR1 (0.89) | S1PR5S1PR1S1PR3S1PR4TNK2 | |
| SCHEMBL565212 | 0.84 | S1PR5 (0.87) | S1PR5S1PR1S1PR3S1PR4 | |
| SCHEMBL3040328 | 0.83 | S1PR1 (0.97) | S1PR5S1PR1S1PR3S1PR4TNK2 | |
| SCHEMBL3933586 | 0.83 | S1PR5 (0.69) | S1PR5S1PR1S1PR3S1PR4 | |
| SCHEMBL992857 | 0.83 | S1PR5 (0.76) | S1PR5S1PR1S1PR3S1PR4 | |
| SCHEMBL3043605 | 0.82 | S1PR5 (1.00) | S1PR5S1PR1S1PR3S1PR4 | |
| SCHEMBL15532870 | 0.82 | S1PR5 (0.69) | S1PR5S1PR1S1PR3S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012074780-A1 | NOVEL OXIME AZETIDINE DERIVATIVES AS SPHINGOSINE 1-PHOSPHATE (S1P) RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2012-06-07 | — | — | WO | disclosed |
| EP-1873153-B1 | 3-AZETIDINECARBOXYLIC ACID DERIVATIVES FOR USE AS IMMUNOSUPPRESSANTS | DAIICHI SANKYO CO LTD (JP) | 2010-07-07 | — | — | EP | disclosed |