Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 10/20 | 0.65 |
| ▸ | KDM4A | O75164 | 3/20 | 0.50 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9915602 | 1.00 | APP (0.65) | APPKDM4AKDM2ACHRM2CHRM4 | |
| SCHEMBL9915601 | 1.00 | APP (0.65) | APPKDM4AKDM2ACHRM2CHRM4 | |
| SCHEMBL9915600 | 0.98 | APP (0.61) | APPKDM4AKDM2ACHRM2CHRM4 | |
| SCHEMBL7717138 | 0.92 | KDM4A (0.58) | APPKDM4AKDM2ACHRM2CHRM4 | |
| SCHEMBL7717137 | 0.92 | KDM4A (0.58) | APPKDM4AKDM2ACHRM2CHRM4 | |
| SCHEMBL3419099 | 0.86 | CHRM2 (0.47) | APPKDM4AKDM2ACHRM2CHRM4 | |
| SCHEMBL3419103 | 0.86 | CHRM2 (0.47) | APPKDM4AKDM2ACHRM2CHRM4 | |
| SCHEMBL16295267 | 0.86 | CHRM2 (0.47) | APPKDM4AKDM2ACHRM2CHRM4 | |
| SCHEMBL13223084 | 0.85 | KDM4A (0.59) | APPKDM4AKDM2ACHRM2CHRM4 | |
| SCHEMBL3045309 | 0.84 | CHRM2 (0.60) | APPKDM4AKDM2ACHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8197722-B2 | Irradiating the compound (containing two electron donor groups and a bridge of pi-conjugated bonds containing electron donor groups) with light, and the compound is converted to a multi-photon electronically excited state | THE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-06-12 | — | — | US | disclosed |
| US-8197722-B2 | Irradiating the compound (containing two electron donor groups and a bridge of pi-conjugated bonds containing electron donor groups) with light, and the compound is converted to a multi-photon electronically excited state | THE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-06-12 | — | — | US | disclosed |