SCHEMBL9915764

SCHEMBL9915764

C=C(C)C(=O)Oc1ccc(/C(=C\c2ccc(N(c3ccc(C)cc3)c3ccc(C)cc3)cc2)c2ccccc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.54
PTGS2 P35354 3/20 0.47
ALDH1A1 P00352 5/20 0.44
MAPT P10636 5/20 0.44
KDM4E B2RXH2 3/20 0.44
KMT2A Q03164 3/20 0.44
HPGD P15428 2/20 0.44
HSP90AA1 P07900 2/20 0.44
MEN1 O00255 1/20 0.44
CYP2D6 P10635 1/20 0.40
NPC1 O15118 1/20 0.39
POLB P06746 1/20 0.39
RAB9A P51151 1/20 0.39
LMNA P02545 3/20 0.39
GAA P10253 1/20 0.37
TRPM8 Q7Z2W7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17427341 1.00 ELANE (0.54) ELANEPTGS2ALDH1A1MAPTKDM4E
SCHEMBL2609807 1.00 ELANE (0.54) ELANEPTGS2ALDH1A1MAPTKDM4E
SCHEMBL9915696 0.99 ELANE (0.52) ELANEPTGS2ALDH1A1MAPTKDM4E
SCHEMBL9915762 0.96 ELANE (0.50) ELANEPTGS2ALDH1A1MAPTKDM4E
SCHEMBL11938797 0.96 ELANE (0.50) ELANEPTGS2ALDH1A1MAPTKDM4E
SCHEMBL9915761 0.94 ELANE (0.58) ELANEPTGS2ALDH1A1MAPTKDM4E
SCHEMBL2609803 0.94 ELANE (0.58) ELANEPTGS2ALDH1A1MAPTKDM4E
SCHEMBL9915694 0.93 ELANE (0.56) ELANEPTGS2ALDH1A1MAPTKDM4E
SCHEMBL13777766 0.90 ELANE (0.44) ELANEPTGS2ALDH1A1MAPTKDM4E
SCHEMBL12395605 0.89 ELANE (0.51) ELANEPTGS2ALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190285997-A1 IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2019-09-19 US disclosed
US-8197997-B2 Electrophotographic photoconductor, production method thereof, image forming method and image forming apparatus using photoconductor, and process cartridge RICOH COMPANY, LTD. (JP) 2012-06-12 US disclosed
US-8197997-B2 Electrophotographic photoconductor, production method thereof, image forming method and image forming apparatus using photoconductor, and process cartridge RICOH COMPANY, LTD. (JP) 2012-06-12 US disclosed
US-8114563-B2 Forming photosensitive layer on electroconductive substrate wherein the crosslinked surface layer has a surface roughness (Ra) not greater than 0.2 mu m and a peel strength not less than 0.2 N/mm; durability, stable electrical properties, good cleanability, and producing high-quality images RICOH COMPANY, LIMITED (JP) 2012-02-14 US disclosed
US-8114563-B2 Forming photosensitive layer on electroconductive substrate wherein the crosslinked surface layer has a surface roughness (Ra) not greater than 0.2 mu m and a peel strength not less than 0.2 N/mm; durability, stable electrical properties, good cleanability, and producing high-quality images RICOH COMPANY, LIMITED (JP) 2012-02-14 US disclosed
US-20090035672-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, PRODUCTION METHOD THEREOF, IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS USING PHOTOCONDUCTOR, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2009-02-05 US disclosed
US-20090035672-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, PRODUCTION METHOD THEREOF, IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS USING PHOTOCONDUCTOR, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2009-02-05 US disclosed
US-20080038649-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PREPARING THE PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE THEREFOR USING THE PHOTORECEPTOR RICOH COMPANY, LIMITED (JP) 2008-02-14 US disclosed
US-20080038649-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PREPARING THE PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE THEREFOR USING THE PHOTORECEPTOR RICOH COMPANY, LIMITED (JP) 2008-02-14 US disclosed
US-20070212627-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PREPARING THE PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE THEREFOR USING THE PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2007-09-13 US disclosed
US-20070212627-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PREPARING THE PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE THEREFOR USING THE PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2007-09-13 US disclosed