⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3907525 | 1.00 | — | — | |
| SCHEMBL1014902 | 1.00 | — | — | |
| SCHEMBL15685990 | 0.82 | HSD17B10 (0.34) | — | |
| SCHEMBL22218617 | 0.80 | HSD17B10 (0.33) | — | |
| SCHEMBL473650 | 0.79 | — | — | |
| SCHEMBL8427554 | 0.78 | — | — | |
| SCHEMBL9394354 | 0.78 | TSHR (0.43) | — | |
| SCHEMBL10592489 | 0.77 | — | — | |
| SCHEMBL538247 | 0.77 | — | — | |
| SCHEMBL12174865 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3247481-B1 | PURIFICATION OF PLASTICIZERS | ARCHER DANIELS MIDLAND CO (US) | 2020-08-12 | — | — | EP | claimed |
| CN-107106933-B | Purification of plasticizers | 阿彻丹尼尔斯米德兰德公司 | 2020-04-14 | — | — | CN | claimed |
| US-20180002301-A1 | PURIFICATION OF PLASTICIZERS | ARCHER DANIELS MIDLAND COMPANY (US) | 2018-01-04 | — | — | US | claimed |
| EP-3247481-A1 | PURIFICATION OF PLASTICIZERS | Archer Daniels Midland Co. (US) | 2017-11-29 | — | — | EP | claimed |
| WO-2016114944-A1 | PURIFICATION OF PLASTICIZERS | ARCHER DANIELS MIDLAND COMPANY (US) | 2016-07-21 | — | — | WO | claimed |
| US-8927539-B2 | Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1 based on the 1,3-oxazinan-2-one structure | VITAE PHARMACEUTICALS, INC. (US) | 2015-01-06 | — | — | US | claimed |
| US-20120208804-A1 | CYCLIC INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE 1 BASED ON THE 1,3 -OXAZINAN- 2 -ONE STRUCTURE | VITAE PHARMACEUTICALS, INC. (US) | 2012-08-16 | — | — | US | claimed |
| EP-2440537-A1 | CYCLIC INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE 1 BASED ON THE 1,3 -OXAZINAN- 2 -ONE STRUCTURE | Vitae Pharmaceuticals, Inc. (US) | 2012-04-18 | — | — | EP | claimed |
| US-7956188-B2 | N-substituted-2-alkylthio-2-(substituted aryloxy and heteroaryloxy)alkylamides and their sulphinyl and sulphonyl derivatives such as 2-(3,5-dichlorophenoxy)-2-methylthio-N-2-methylprop-2-yl acetamide; fungal infections of plants | SYNGENTA CROP PROTECTION, INC. (US) | 2011-06-07 | — | — | US | claimed |
| WO-2011011123-A1 | CYCLIC INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE 1 BASED ON THE 1,3 -OXAZINAN- 2 -ONE STRUCTURE | VITAE PHARMACEUTICALS, INC. (US) | 2011-01-27 | — | — | WO | claimed |
| EP-1817309-B1 | ACETAMIDE COMPOUNDS AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-12-23 | — | — | EP | claimed |
| US-20080171767-A1 | N-substituted-2-alkylthio-2-(substituted aryloxy and heteroaryloxy)alkylamides and their sulphinyl and sulphonyl derivatives such as 2-(3,5-dichlorophenoxy)-2-methylthio-N-2-methylprop-2-yl acetamide; fungal infections of plants | SYNGENTA CROP PROTECTION, INC. (US) | 2008-07-17 | — | — | US | claimed |
| US-6531635-B1 | Hydrolyzing and hydrogenating a reaction mixture of 1,1,3-trialkoxyalkane and 3-alkoxyalkanal obtained from reaction of an alpha,beta-unsaturated aldehyde with an alcohol; 3-methoxypropanol from acrolein and methanol | IDEMITSU PETROCHEMICALS CO., LTD. (JP) | 2003-03-11 | — | — | US | claimed |
| US-11820864-B2 | Aqueous polyglycidol synthesis with ultra-low branching | VANDERBILT UNIVERSITY (US) | 2023-11-21 | — | — | US | disclosed |
| WO-2021180002-A1 | METHOD FOR PREPARING ALKYL HYDROXYL ACID ESTER AND USE THEREOF | HUANG EDWIN W (CN) | 2021-09-16 | — | — | WO | disclosed |
| US-10745368-B2 | Purification of plasticizers | ARCHER DANIELS MIDLAND COMPANY (US) | 2020-08-18 | — | — | US | disclosed |
| US-4795814-A | CORONARY VASODILATORS, HYPOTENSIVE AGENTS, ANTIINFLAMMATORY AGENTS, ANTITUMOR AGENTTS, ENZYME INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-01-03 | — | — | US | disclosed |
| EP-0239129-A2 | Hydroquinoline compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-09-30 | — | — | EP | disclosed |
| EP-0173126-A1 | Process for preparing novel dihydropyridine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-03-05 | — | — | EP | disclosed |
| EP-0145434-A2 | Novel dihydropyridine derivatives and process for preparing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-06-19 | — | — | EP | disclosed |