⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL991978 | 0.67 | — | — | |
| SCHEMBL30083659 | 0.57 | — | — | |
| SCHEMBL3891310 | 0.56 | — | — | |
| SCHEMBL25404221 | 0.55 | — | — | |
| SCHEMBL19133 | 0.55 | — | — | |
| SCHEMBL20716 | 0.53 | — | — | |
| SCHEMBL2958765 | 0.52 | — | — | |
| SCHEMBL2065365 | 0.52 | — | — | |
| Hydrazine SCHEMBL6947918 | 0.52 | — | — | |
| SCHEMBL15048602 | 0.47 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107098934-B | A kind of method of phthalic aldehyde derivative phosphoramidite monomer, synthetic method and the quick coupling protein matter of DNA | 厦门大学 | 2019-03-12 | — | — | CN | claimed |
| CN-109265486-A | A kind of compound and its preparation method and application of the element of base containing ferrocene | 湖南大学 | 2019-01-25 | — | — | CN | claimed |
| CN-107698641-A | DNA with terminal group modified by sulfur and preparation method thereof | 中国石油大学(华东) | 2018-02-16 | — | — | CN | claimed |
| CN-107674094-A | Phosphoramidite lipol ester and synthesis method and application thereof | 中国石油大学(华东) | 2018-02-09 | — | — | CN | claimed |
| CN-107098934-A | A kind of method of phthalic aldehyde derivative phosphoramidite monomer, synthetic method and the quick coupling protein matter of DNA | 厦门大学 | 2017-08-29 | — | — | CN | claimed |
| CN-105693772-B | A kind of compound and its application in DNA end group modifications | 中国石油大学(华东) | 2017-03-15 | — | — | CN | claimed |
| CN-101238213-B | Stable and selective formation of hoogsteen-type triplexes and duplexes using twisted intercalating nucleic acids (TINA) and process for the preparation of tina | TINA HOLDING APS | 2015-05-20 | — | — | CN | claimed |
| CN-103408624-A | Method for synthesizing nucleotide phosphoramidate and nucleotide thio-phosphoramidate | UNIV JIANGXI NORMAL SCI & TECH | 2013-11-27 | — | — | CN | claimed |
| CN-1847288-B | Polymeric phosphite composition and hydrocyanation of unsaturated organic compounds and the isomerization of unsaturated nitriles | INVISTA TECH SARL | 2011-06-15 | — | — | CN | claimed |
| CN-101238213-A | Stable and selective formation of hoogsteen-type triplexes and duplexes using twisted intercalating nucleic acids (TINA) and process for the preparation of tina | TINA HOLDING APS (DK) | 2008-08-06 | — | — | CN | claimed |
| CN-1847288-A | Polymeric phosphite composition and hydrocyanation of unsaturated organic compounds and the isomerization of unsaturated nitriles | INVISTA TECH SARL (CH) | 2006-10-18 | — | — | CN | claimed |
| CN-1390241-A | Polymeric phosphite compositions and hydrocyanation of unsaturated organic compounds and isomerization of unsaturated nitriles | DU PONT (US) | 2003-01-08 | — | — | CN | claimed |
| CN-118666926-A | Glycosyl phosphoramidite monomer, preparation method thereof and synthesis method of glycosyl oligonucleotide | 上海交通大学医学院附属仁济医院 | 2024-09-20 | — | — | CN | disclosed |
| US-10465242-B2 | Multi-sequence capture system | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2019-11-05 | — | — | US | disclosed |
| CN-109810141-A | Sulfur-bearing phosphorous imide ester, preparation method and its application | 中国石油大学(华东) | 2019-05-28 | — | — | CN | disclosed |
| CN-109689063-A | Nucleotide containing alkynes and nucleosides therapeutic combination and its associated uses | 埃默里大学 | 2019-04-26 | — | — | CN | disclosed |
| CN-1353719-A | Novel phosphorus-containing prodrugs | METABASIS THERAPEUTICS INC (US) | 2002-06-12 | — | — | CN | disclosed |
| EP-1165570-A2 | NOVEL PHOSPHORUS-CONTAINING PRODRUGS | Metabasis Therapeutics, Inc. (US) | 2002-01-02 | — | — | EP | disclosed |
| CN-1270598-A | Methods and compounds for analyzing nucleic acids by mass spectrometry | RAPIGENE INC (US) | 2000-10-18 | — | — | CN | disclosed |
| WO-2000052015-A2 | NOVEL PHOSPHORUS-CONTAINING PRODRUGS | METABASIS THERAPEUTICS, INC. (US) | 2000-09-08 | — | — | WO | disclosed |