Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.32 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14311330 | 0.84 | CA12 (0.38) | CA12CA1CA2CA9HDAC6 | |
| SCHEMBL5001089 | 0.84 | CA12 (0.55) | CA12CA1CA2CA9HDAC6 | |
| SCHEMBL1689401 | 0.83 | HDAC6 (0.37) | CA12CA1CA2CA9HDAC6 | |
| SCHEMBL15487077 | 0.82 | CA12 (0.37) | CA12CA1CA2CA9HDAC6 | |
| SCHEMBL3187773 | 0.81 | HDAC6 (0.36) | CA12CA1CA2CA9HDAC6 | |
| SCHEMBL20117509 | 0.81 | CA12 (0.36) | CA12CA1CA2CA9HDAC6 | |
| SCHEMBL14789144 | 0.79 | HDAC6 (0.35) | CA12CA1CA2CA9HDAC6 | |
| SCHEMBL7023795 | 0.79 | CA14 (0.39) | CA12CA1CA2CA9HDAC6 | |
| SCHEMBL398901 | 0.79 | CA12 (0.50) | CA12CA1CA2CA9HDAC6 | |
| SCHEMBL25382768 | 0.78 | TLR2 (0.38) | CA12CA1CA2CA9HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011011483-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2011-01-27 | — | — | WO | disclosed |