SCHEMBL9920504

SCHEMBL9920504

c1ccc(-c2nc(-c3cccc(-c4nc(-c5ccccc5)c5ccccc5n4)c3)nc3ccccc23)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.67
KMT2A Q03164 3/20 0.67
ATM Q13315 1/20 0.67
WHR1 P49842 1/20 0.57
NUDT1 P36639 3/20 0.56
ADORA2A P29274 3/20 0.56
MAPT P10636 3/20 0.51
GAA P10253 1/20 0.51
NR1I3 Q14994 4/20 0.50
ALDH1A1 P00352 3/20 0.50
CYP1A2 P05177 3/20 0.50
CYP3A4 P08684 3/20 0.50
CYP2C9 P11712 3/20 0.50
KDM4E B2RXH2 2/20 0.50
CYP2B6 P20813 2/20 0.50
AHR P35869 2/20 0.50
HPGD P15428 2/20 0.50
VDR P11473 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
LMNA P02545 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18503958 0.96 MEN1 (0.63) MEN1KMT2AATMWHR1NUDT1
SCHEMBL18504010 0.95 MEN1 (0.61) MEN1KMT2AATMWHR1NUDT1
SCHEMBL18503954 0.95 MEN1 (0.66) MEN1KMT2AATMWHR1NUDT1
SCHEMBL24084022 0.95 MEN1 (0.66) MEN1KMT2AATMWHR1NUDT1
SCHEMBL24084045 0.95 MEN1 (0.61) MEN1KMT2AATMWHR1NUDT1
SCHEMBL12014869 0.94 MEN1 (0.69) MEN1KMT2AATMWHR1NUDT1
SCHEMBL31065527 0.93 MEN1 (0.59) MEN1KMT2AATMWHR1NUDT1
SCHEMBL18504016 0.93 MEN1 (0.64) MEN1KMT2AATMWHR1NUDT1
SCHEMBL24084040 0.93 MEN1 (0.58) MEN1KMT2AATMWHR1NUDT1
SCHEMBL23606772 0.93 MEN1 (0.68) MEN1KMT2AATMWHR1NUDT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1947707-B1 ORGANIC ELECTROLUMINESCENT ELEMENT, LIQUID CRYSTAL DISPLAY DEVICE, AND LIGHTING EQUIPMENT KONICA MINOLTA HOLDINGS INC (JP) 2017-04-26 EP disclosed
EP-2651904-B1 BISPYRIMIDINES FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2014-11-12 EP disclosed
US-8362246-B2 Bispyrimidines for electronic applications BASF SE (DE) 2013-01-29 US disclosed
US-8362246-B2 Bispyrimidines for electronic applications BASF SE (DE) 2013-01-29 US disclosed
US-8310146-B2 Organic electroluminescent device, liquid crystal display and illuminating device KONICA MINOLTA HOLDINGS, INC. (JP) 2012-11-13 US disclosed
US-8310146-B2 Organic electroluminescent device, liquid crystal display and illuminating device KONICA MINOLTA HOLDINGS, INC. (JP) 2012-11-13 US disclosed
WO-2012080052-A1 BISPYRIMIDINES FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2012-06-21 WO disclosed
US-20120149904-A1 BISPYRIMIDINES FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2012-06-14 US disclosed
US-20120149904-A1 BISPYRIMIDINES FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2012-06-14 US disclosed
US-20090279285-A1 ORGANIC ELECTROLUMINESCENT DEVICE, LIQUID CRYSTAL DISPLAY AND ILLUMINATING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2009-11-12 US disclosed
US-20090279285-A1 ORGANIC ELECTROLUMINESCENT DEVICE, LIQUID CRYSTAL DISPLAY AND ILLUMINATING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2009-11-12 US disclosed
EP-1947707-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, LIQUID CRYSTAL DISPLAY DEVICE, AND LIGHTING EQUIPMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2008-07-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120149904-A1 BISPYRIMIDINES FOR ELECTRONIC APPLICATIONS DPYD, TYMP, TYMS MEN1 3376/4885KMT2A 2215/4885ATM 2950/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.