Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD1 | Q15139 | 6/20 | 0.61 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.61 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.61 |
| ▸ | CDK1 | P06493 | 3/20 | 0.58 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9919702 | 0.76 | PRKD1 (0.71) | PRKD1PRKD2PRKD3CDK1MAPKAPK2 | |
| SCHEMBL29920016 | 0.76 | PRKD1 (1.00) | PRKD1PRKD2PRKD3CDK1MAPKAPK2 | |
| SCHEMBL15472000 | 0.76 | PRKD1 (0.71) | PRKD1PRKD2PRKD3CDK1MAPKAPK2 | |
| SCHEMBL9920595 | 0.76 | PRKD1 (1.00) | PRKD1PRKD2PRKD3CDK1MAPKAPK2 | |
| SCHEMBL9920647 | 0.76 | PRKD1 (0.67) | PRKD1PRKD2PRKD3CDK1MAPKAPK2 | |
| SCHEMBL6651109 | 0.73 | MAPKAPK2 (1.00) | PRKD1PRKD2PRKD3CDK1MAPKAPK2 | |
| SCHEMBL9904371 | 0.71 | MAPKAPK2 (0.74) | PRKD1PRKD2PRKD3CDK1MAPKAPK2 | |
| SCHEMBL15465380 | 0.71 | PRKD1 (1.00) | PRKD1PRKD2PRKD3CDK1MAPKAPK2 | |
| SCHEMBL9920611 | 0.71 | PRKD1 (0.62) | PRKD1PRKD2PRKD3CDK1MAPKAPK2 | |
| SCHEMBL9920607 | 0.69 | PRKD1 (1.00) | PRKD1PRKD2PRKD3CDK1MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012078859-A2 | PROTEIN KINASE D INHIBITORS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2012-06-14 | — | — | WO | disclosed |