Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 18/20 | 0.62 |
| ▸ | PPARG | P37231 | 3/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5959666 | 0.97 | PPARD (0.66) | PPARDPPARGPPARA | |
| SCHEMBL5959713 | 0.95 | PPARD (0.59) | PPARDPPARGPPARA | |
| SCHEMBL1746440 | 0.91 | PPARD (0.57) | PPARDPPARGPPARAKDM4ELMNA | |
| SCHEMBL1746442 | 0.91 | PPARD (0.57) | PPARDPPARGPPARAKDM4ELMNA | |
| SCHEMBL1746437 | 0.91 | PPARD (0.57) | PPARDPPARGPPARAKDM4ELMNA | |
| SCHEMBL5959448 | 0.91 | PPARD (0.61) | PPARDPPARGPPARA | |
| SCHEMBL4330699 | 0.88 | PPARD (0.55) | PPARDPPARGPPARA | |
| SCHEMBL4330702 | 0.88 | PPARD (0.55) | PPARDPPARGPPARA | |
| SCHEMBL1747341 | 0.88 | PPARD (0.62) | PPARDPPARG | |
| SCHEMBL1747343 | 0.88 | PPARD (0.62) | PPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979311-B1 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | HIGH POINT PHARMACEUTICALS LLC (US) | 2012-06-13 | — | — | EP | disclosed |
| EP-2386540-A1 | Novel compounds, their preparation and use | High Point Pharmaceuticals, LLC (US) | 2011-11-16 | — | — | EP | disclosed |
| WO-2007071766-A2 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | TRANSTECH PHARMA (US) | 2007-06-28 | — | — | WO | disclosed |