Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 17/20 | 0.43 |
| ▸ | PPARG | P37231 | 14/20 | 0.40 |
| ▸ | PPARA | Q07869 | 13/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4334801 | 0.81 | PPARD (0.61) | PPARDPPARGPPARAFFAR1 | |
| SCHEMBL4334798 | 0.81 | PPARD (0.61) | PPARDPPARGPPARAFFAR1 | |
| SCHEMBL4325528 | 0.81 | PPARD (0.47) | PPARDPPARGPPARAFFAR1 | |
| SCHEMBL12159999 | 0.77 | PPARD (0.50) | PPARDPPARGPPARA | |
| SCHEMBL9921098 | 0.77 | POLB (0.46) | PPARD | |
| SCHEMBL12160165 | 0.77 | POLB (0.46) | PPARD | |
| SCHEMBL14495856 | 0.76 | PPARD (0.44) | PPARDPPARGPPARAFFAR1 | |
| SCHEMBL12160118 | 0.73 | PPARD (0.54) | PPARDPPARGPPARA | |
| SCHEMBL6474183 | 0.73 | PPARD (0.77) | PPARDPPARGPPARAFFAR1 | |
| SCHEMBL1745143 | 0.70 | KDM4E (0.46) | PPARDPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979311-B1 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | HIGH POINT PHARMACEUTICALS LLC (US) | 2012-06-13 | — | — | EP | disclosed |