Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14214203 | 0.96 | GRIN1 (0.31) | GRIN1GRIN2B | |
| SCHEMBL9921559 | 0.89 | — | — | |
| SCHEMBL9905142 | 0.88 | GRIN1 (0.31) | GRIN1GRIN2B | |
| SCHEMBL9921536 | 0.87 | GRIN1 (0.34) | GRIN1GRIN2B | |
| SCHEMBL9921619 | 0.86 | — | — | |
| SCHEMBL9921571 | 0.85 | — | — | |
| SCHEMBL14214206 | 0.85 | — | — | |
| SCHEMBL14214200 | 0.83 | GRIN1 (0.33) | GRIN1GRIN2B | |
| SCHEMBL14214199 | 0.82 | — | — | |
| SCHEMBL9921576 | 0.82 | NTRK1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846659-B2 | HIV integrase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-09-30 | — | — | US | disclosed |
| US-8846659-B2 | HIV integrase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-09-30 | — | — | US | disclosed |
| WO-2012078844-A1 | HIV INTEGRASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-06-14 | — | — | WO | disclosed |