Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3415829 | 1.00 | GRM5 (0.77) | GRM5HPGD | |
| SCHEMBL991034 | 0.90 | GRM5 (0.81) | GRM5HPGD | |
| SCHEMBL990813 | 0.87 | GRM5 (1.00) | GRM5HPGD | |
| SCHEMBL990910 | 0.87 | GRM5 (1.00) | GRM5HPGD | |
| SCHEMBL991547 | 0.85 | GRM5 (0.76) | GRM5HPGD | |
| SCHEMBL991523 | 0.85 | GRM5 (0.76) | GRM5HPGD | |
| SCHEMBL990274 | 0.83 | GRM5 (0.71) | GRM5HPGD | |
| SCHEMBL990217 | 0.83 | GRM5 (0.71) | GRM5HPGD | |
| SCHEMBL990918 | 0.79 | GRM5 (1.00) | GRM5HPGD | |
| SCHEMBL990190 | 0.79 | GRM5 (1.00) | GRM5HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090005363-A1 | Organic Compounds | NOVARTIS AG (CH) | 2009-01-01 | — | — | US | claimed |
| EP-2272509-A1 | New Uses of metabotropic glutamate receptors | Novartis AG (CH) | 2011-01-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005363-A1 | Organic Compounds | NNT, NAPRT, CHRNA5 | GRM5 680/4885HPGD 280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.