Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9923344 | 0.79 | CDK2 (0.40) | CDK2 | |
| SCHEMBL16503594 | 0.79 | CDK2 (0.46) | CDK2 | |
| SCHEMBL9923287 | 0.72 | CDK2 (0.60) | CDK2EPHB3 | |
| SCHEMBL9923282 | 0.70 | CDK2 (0.41) | CDK2EPHB3 | |
| SCHEMBL9920402 | 0.69 | — | — | |
| SCHEMBL9923417 | 0.69 | MEN1 (0.36) | CDK2 | |
| SCHEMBL9923350 | 0.68 | CDK2 (0.39) | CDK2 | |
| SCHEMBL1160399 | 0.67 | CDK2 (0.49) | CDK2EPHB3 | |
| SCHEMBL21855498 | 0.64 | CDK2 (0.54) | CDK2 | |
| SCHEMBL12681980 | 0.63 | CDK2 (0.35) | CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149691-A1 | Pyrrolo [1,2-b] Pyridazine Derivatives as Janus Kinase Inhibitors | BIOCRYST PHARMACEUTICALS, INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149691-A1 | Pyrrolo [1,2-b] Pyridazine Derivatives as Janus Kinase Inhibitors | JAK1, JAK2, JAK3 | CDK2 423/4885EPHB3 3982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.