⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9923597 | 1.00 | — | — | |
| SCHEMBL9923596 | 1.00 | — | — | |
| Water SCHEMBL11658973 | 0.98 | CA1 (0.39) | — | |
| SCHEMBL10453888 | 0.93 | — | — | |
| SCHEMBL9049879 | 0.87 | — | — | |
| SCHEMBL183398 | 0.87 | — | — | |
| SCHEMBL8451957 | 0.72 | — | — | |
| SCHEMBL16385879 | 0.70 | — | — | |
| SCHEMBL16385813 | 0.70 | — | — | |
| SCHEMBL4749913 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240400556-A1 | AMIDOPYRIMIDONE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2024-12-05 | — | — | US | disclosed |
| EP-3786144-B1 | PRODUCTION METHOD FOR 1,4-BUTANEDIOL | MITSUBISHI CHEM CORP (JP) | 2023-09-06 | — | — | EP | disclosed |
| US-20230227449-A1 | AMIDOPYRIMIDONE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2023-07-20 | — | — | US | disclosed |
| EP-4168394-A1 | AMIDOPYRIMIDONE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2023-04-26 | — | — | EP | disclosed |
| CN-115867541-A | Aminopyrimidinone derivatives | 豪夫迈·罗氏有限公司 | 2023-03-28 | — | — | CN | disclosed |
| WO-2021259815-A1 | AMIDOPYRIMIDONE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2021-12-30 | — | — | WO | disclosed |
| US-10954336-B2 | Cyclic poly L-lactic acid | SCRUM CO., LTD. (JP) | 2021-03-23 | — | — | US | disclosed |
| EP-3786144-A1 | PRODUCTION METHOD FOR 1,4-BUTANEDIOL | Mitsubishi Chemical Corporation (JP) | 2021-03-03 | — | — | EP | disclosed |
| EP-3517521-B1 | PRODUCTION METHOD FOR 1,4-BUTANEDIOL | MITSUBISHI CHEM CORP (JP) | 2020-12-09 | — | — | EP | disclosed |
| CN-107602824-B | Process for producing polyester and polyurethane | 基因组股份公司 | 2020-11-13 | — | — | CN | disclosed |
| EP-2862886-A1 | POLYESTER AND POLYURETHANE PRODUCTION METHOD | Mitsubishi Chemical Corporation (JP) | 2015-04-22 | — | — | EP | disclosed |
| EP-2857377-A1 | PRODUCTION METHOD FOR 1, 4-BUTANEDIOL | Mitsubishi Chemical Corporation (JP) | 2015-04-08 | — | — | EP | disclosed |
| US-20150087038-A1 | PRODUCTION METHOD FOR 1,4-BUTANEDIOL | MITSUBISHI CHEMICAL CORPORATION (JP) | 2015-03-26 | — | — | US | disclosed |
| US-20150087789-A1 | PRODUCTION METHODS OF POLYESTER AND POLYURETHANE | MITSUBISHI CHEMICAL CORPORATION (JP) | 2015-03-26 | — | — | US | disclosed |
| US-8957229-B2 | Method for the production of a mixture of lactide derivatives | UHDE INVENTA-FISCHER GMBH (DE) | 2015-02-17 | — | — | US | disclosed |
| US-20140323468-A1 | ALDOSTERONE SYNTHASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-10-30 | — | — | US | disclosed |
| EP-2392570-B1 | Method for manufacturing a mixture of lactide derivatives | UHDE INVENTA FISCHER GMBH (DE) | 2014-10-01 | — | — | EP | disclosed |
| US-20120149920-A1 | Method for the production of a mixture of lactide derivatives | UHDE GMBH (DE) | 2012-06-14 | — | — | US | disclosed |
| US-20120040935-A1 | COMPOSITIONS USEFUL AS INHIBITORS OF VOLTAGE-GATED ION CHANNELS | VERTEX PHARMACEUTICALS, INC. (US) | 2012-02-16 | — | — | US | disclosed |
| US-7968545-B2 | Compositions useful as inhibitors of voltage-gated ion channels | VERTEX PHARMACEUTICALS INC. (US) | 2011-06-28 | — | — | US | disclosed |